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FLC3 protein (Saccharomyces cerevisiae) - STRING interaction network
"FLC3" - Putative FAD transporter, similar to Flc1p and Flc2p in Saccharomyces cerevisiae
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FLC3Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER; May be responsible for the transport of FAD into the endoplasmic reticulum lumen, where it is required for oxidative protein folding (802 aa)    
Predicted Functional Partners:
YGL140C
Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains (1219 aa)
     
   
  0.818
RRT6
Putative protein of unknown function; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; contains two putative transmembrane spans, but no significant homology to other known proteins; May be involved in the modulation of rDNA transcription (311 aa)
           
  0.626
YPR076W
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data (124 aa)
           
  0.579
MYO2
One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; Myosin heavy chain that is required for the cell cycle- regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables. Essential for the [...] (1574 aa)
       
      0.518
SSP120
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern (234 aa)
           
  0.511
YMR187C
Putative protein of unknown function; YMR187C is not an essential gene (431 aa)
           
  0.505
YNL011C
Putative protein of unknown function; YNL011C is not an essential gene (444 aa)
           
  0.503
ERO1
Thiol oxidase required for oxidative protein folding in the endoplasmic reticulum; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI1 isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI1 to transfer oxidizing equivalent. Also able to oxidize directly the PDI related protein MPD2. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI1 and related proteins. Reoxidation of ERO1 probably involves elect [...] (563 aa)
           
  0.500
RHO1
GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p); Acts as a central regulator in the cell wall integrity signaling pathway, which is regulated by the cell cycle and in response to various types of cell wall stress. Integrates signals from different cell surface sensors, and activates a set of effectors, regulating processes including beta-glucan synthesis at the site of wall remodeling, gene expression related to c [...] (209 aa)
       
      0.473
VPS68
Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria; Involved in vacuolar protein sorting (184 aa)
           
  0.452
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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