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SPO74 protein (Saccharomyces cerevisiae) - STRING interaction network
"SPO74" - Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation in Saccharomyces cerevisiae
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SPO74Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation; Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Probable component of a core structural unit of the scaffold that initiates synthesis of the prospore membrane (413 aa)    
Predicted Functional Partners:
SPO21
Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation; Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May provide a meiosis-specific scaffold for the assembly of other proteins on spindle pole bodies (SPBs), and may be a limiting component for SPB formation (609 aa)
       
 
  0.962
MPC54
Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate; Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation (464 aa)
       
 
  0.960
ADY4
Structural component of the meiotic outer plaque, which is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May be required to stabilize the outer plaque of the spindle pole body (SPB) (493 aa)
           
  0.922
PFS1
Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation; Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. Required to localize MPC54 to all four spindle pole bodies, and localize DON1 and SPO14 to four prospore membranes (237 aa)
     
 
  0.832
SSP1
Protein involved in the control of meiotic nuclear division and coordination of meiosis with spore formation; transcription is induced midway through meiosis; Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May be required for the formation of ADY3 and DON1-containing protein coats at the leading edge of the PSMs during meiosis II (571 aa)
           
  0.739
DTR1
Putative dityrosine transporter, required for spore wall synthesis; expressed during sporulation; member of the major facilitator superfamily (DHA1 family) of multidrug resistance transporters; Prospore-specific dityrosine transporter responsible for translocation of dityrosine through the prospore membrane and required for the formation of the outermost layer of the spore (572 aa)
     
   
  0.716
NUP116
Subunit of the Nup82 subcomplex of the nuclear pore complex; localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for [...] (1113 aa)
       
      0.704
DON1
Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II; Involved in the pathway that organizes the prospore membrane (PSM) during sporulation (365 aa)
           
  0.697
SPO20
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog; Required to maintain the prospore membrane to the nucleus during sporulation in order to capture the daughter nuclei and form the spores. Mediates the fusion of exocytic vesicles with the plasma membrane during sporulation through its interactions with the t-SNARE SSO1 and v-SNARE SNC2 (397 aa)
     
   
  0.658
CDC4
F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins. Directs ubiquitination of the phosphorylated CDK inhibitor SIC1. Involved in the degradation of CDC6 together with CDC [...] (779 aa)
       
      0.621
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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