Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YGL188CPutative uncharacterized protein YGL188C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. (57 aa)    
Predicted Functional Partners:
YDR003W-A
Uncharacterized protein YDR003W-A; Putative protein of unknown function; identified by expression profiling and mass spectrometry.
   
    0.522
YDR510C-A
Putative uncharacterized protein YDR510C-A; Dubious open reading frame unlikely to encode a functional protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching.
   
    0.520
COX9
Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain.
   
    0.515
YDR524W-C
Uncharacterized protein YDR524W-C; Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin.
   
    0.514
NCE101
Non-classical export protein 1; Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol; Belongs to the NCE101 family.
   
    0.514
YLR285C-A
Uncharacterized protein YLR285C-A; Putative protein of unknown function; identified by fungal homology and RT-PCR.
   
    0.514
ATP18
Subunit of the mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms.
   
    0.514
YDR034C-A
Putative protein of unknown function; contained within the solo Ty1 LTR element YDRWdelta7.
   
    0.513
YER138W-A
Putative protein of unknown function; YER138W-A has a paralog, YBL107W-A, that arose from a single-locus duplication.
   
    0.513
YHR175W-A
Uncharacterized membrane protein YHR175W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR.
   
    0.513
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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