node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NCA3 | YGL188C-A | YJL116C | YGL188C-A | Protein involved in mitochondrion organization; functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the vacuole; member of the SUN family; expression induced in cells treated with the mycotoxin patulin; NCA3 has a paralog, UTH1, that arose from the whole genome duplication. | Uncharacterized protein YGL188C-A; Putative protein of unknown function. | 0.538 |
NCA3 | YKL068W-A | YJL116C | YKL068W-A | Protein involved in mitochondrion organization; functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the vacuole; member of the SUN family; expression induced in cells treated with the mycotoxin patulin; NCA3 has a paralog, UTH1, that arose from the whole genome duplication. | Uncharacterized protein YKL068W-A; Putative protein of unknown function; identified by homology to <i>Ashbya gossypii</i>. | 0.456 |
SIM1 | TOM5 | YIL123W | YPR133W-A | Probable secreted beta-glucosidase SIM1; Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication. | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | 0.449 |
SIM1 | TOS4 | YIL123W | YLR183C | Probable secreted beta-glucosidase SIM1; Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication. | Protein TOS4; Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress. | 0.525 |
SIM1 | YGL188C-A | YIL123W | YGL188C-A | Probable secreted beta-glucosidase SIM1; Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication. | Uncharacterized protein YGL188C-A; Putative protein of unknown function. | 0.836 |
SIM1 | YKL068W-A | YIL123W | YKL068W-A | Probable secreted beta-glucosidase SIM1; Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication. | Uncharacterized protein YKL068W-A; Putative protein of unknown function; identified by homology to <i>Ashbya gossypii</i>. | 0.791 |
SUN4 | YGL188C-A | YNL066W | YGL188C-A | Probable secreted beta-glucosidase SUN4; Cell wall protein related to glucanases; possibly involved in cell wall septation; member of the SUN family; SUN4 has a paralog, SIM1, that arose from the whole genome duplication. | Uncharacterized protein YGL188C-A; Putative protein of unknown function. | 0.536 |
SUN4 | YKL068W-A | YNL066W | YKL068W-A | Probable secreted beta-glucosidase SUN4; Cell wall protein related to glucanases; possibly involved in cell wall septation; member of the SUN family; SUN4 has a paralog, SIM1, that arose from the whole genome duplication. | Uncharacterized protein YKL068W-A; Putative protein of unknown function; identified by homology to <i>Ashbya gossypii</i>. | 0.512 |
TOM5 | SIM1 | YPR133W-A | YIL123W | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | Probable secreted beta-glucosidase SIM1; Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication. | 0.449 |
TOM5 | YBR196C-B | YPR133W-A | YBR196C-B | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | Uncharacterized protein YBR196C-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | 0.447 |
TOM5 | YGL188C-A | YPR133W-A | YGL188C-A | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | Uncharacterized protein YGL188C-A; Putative protein of unknown function. | 0.498 |
TOM5 | YJL127W-A | YPR133W-A | YJL127W-A | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | Putative uncharacterized protein YJL127W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.445 |
TOM5 | YLR264C-A | YPR133W-A | YLR264C-A | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | Putative protein of unknown function. | 0.695 |
TOS4 | SIM1 | YLR183C | YIL123W | Protein TOS4; Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress. | Probable secreted beta-glucosidase SIM1; Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication. | 0.525 |
TOS4 | YGL188C-A | YLR183C | YGL188C-A | Protein TOS4; Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress. | Uncharacterized protein YGL188C-A; Putative protein of unknown function. | 0.537 |
TOS4 | YKL068W-A | YLR183C | YKL068W-A | Protein TOS4; Putative transcription factor, contains Forkhead Associated domain; binds chromatin; involved in expression homeostasis, buffering of mRNA synthesis rate against gene dosage changes during S phase; target of SBF transcription factor; expression is periodic and peaks in G1; involved in DNA replication checkpoint response; interacts with Rpd3 and Set3 histone deacetylase complexes; APCC(Cdh1) substrate; relative distribution to nucleus increases upon DNA replication stress. | Uncharacterized protein YKL068W-A; Putative protein of unknown function; identified by homology to <i>Ashbya gossypii</i>. | 0.414 |
YBR196C-B | TOM5 | YBR196C-B | YPR133W-A | Uncharacterized protein YBR196C-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | Mitochondrial import receptor subunit TOM5; Component of the TOM (translocase of outer membrane) complex; responsible for recognition and initial import of all mitochondrially directed proteins; involved in transfer of precursors from the Tom70p and Tom20p receptors to the Tom40p pore; Belongs to the Tom5 family. | 0.447 |
YBR196C-B | YGL188C-A | YBR196C-B | YGL188C-A | Uncharacterized protein YBR196C-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | Uncharacterized protein YGL188C-A; Putative protein of unknown function. | 0.446 |
YBR196C-B | YJL127W-A | YBR196C-B | YJL127W-A | Uncharacterized protein YBR196C-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | Putative uncharacterized protein YJL127W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.453 |
YBR196C-B | YLR264C-A | YBR196C-B | YLR264C-A | Uncharacterized protein YBR196C-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | Putative protein of unknown function. | 0.453 |