node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIM2 | RTK1 | YAL049C | YDL025C | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress. | 0.773 |
AIM2 | TDA3 | YAL049C | YHR009C | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1. | 0.724 |
AIM2 | YGR016W | YAL049C | YGR016W | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | 0.904 |
NAT1 | YGR016W | YDL040C | YGR016W | Subunit of protein N-terminal acetyltransferase NatA; NatA comprised of Nat1p, Ard1p, and Nat5p; N-terminally acetylates many proteins to influence multiple processes such as cell cycle progression, heat-shock resistance, mating, sporulation, telomeric silencing and early stages of mitophagy; orthologous to human NAA15; expression of both human NAA10 and NAA15 functionally complements ard1 nat1 double mutant although single mutations are not complemented by their orthologs. | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | 0.449 |
RTK1 | AIM2 | YDL025C | YAL049C | Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress. | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | 0.773 |
RTK1 | TDA3 | YDL025C | YHR009C | Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress. | Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1. | 0.771 |
RTK1 | YGR016W | YDL025C | YGR016W | Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress. | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | 0.919 |
TDA3 | AIM2 | YHR009C | YAL049C | Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1. | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | 0.724 |
TDA3 | RTK1 | YHR009C | YDL025C | Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1. | Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress. | 0.771 |
TDA3 | YGR016W | YHR009C | YGR016W | Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1. | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | 0.898 |
YGR016W | AIM2 | YGR016W | YAL049C | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor; Belongs to the AIM2 family. | 0.904 |
YGR016W | NAT1 | YGR016W | YDL040C | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | Subunit of protein N-terminal acetyltransferase NatA; NatA comprised of Nat1p, Ard1p, and Nat5p; N-terminally acetylates many proteins to influence multiple processes such as cell cycle progression, heat-shock resistance, mating, sporulation, telomeric silencing and early stages of mitophagy; orthologous to human NAA15; expression of both human NAA10 and NAA15 functionally complements ard1 nat1 double mutant although single mutations are not complemented by their orthologs. | 0.449 |
YGR016W | RTK1 | YGR016W | YDL025C | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | Probable serine/threonine-protein kinase RTK1; Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress. | 0.919 |
YGR016W | TDA3 | YGR016W | YHR009C | Uncharacterized membrane protein YGR016W; Putative protein of unknown function. | Putative oxidoreductase involved in late endosome to Golgi transport; physical and genetical interactions with Btn2p; null mutant is viable, has extended S phase, and sensitive to expression of top1-T722A allele; similar to human FOXRED1. | 0.898 |