node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ELO1 | YGR050C | YJL196C | YGR050C | Elongation of fatty acids protein 1; Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.597 |
FRE4 | YGR050C | YNR060W | YGR050C | Ferric reductase transmembrane component 4; Ferric reductase; reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.639 |
GSY1 | SGA1 | YFR015C | YIL099W | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | 0.565 |
GSY1 | YGR050C | YFR015C | YGR050C | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.520 |
ICY1 | YGR050C | YMR195W | YGR050C | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.805 |
NDE1 | YGR050C | YMR145C | YGR050C | Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.518 |
PRY3 | YGR050C | YJL078C | YGR050C | Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.755 |
RSB1 | YGR050C | YOR049C | YGR050C | Putative sphingoid long-chain base (LCB) efflux transporter; integral membrane transporter that localizes to the plasma membrane and may transport long chain bases (LCBs) from the cytoplasmic side toward the extracytoplasmic side of the membrane; role in glycerophospholipid translocation; suppressor of the sphingoid LCB sensitivity of an LCB-lyase mutation. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.697 |
SGA1 | GSY1 | YIL099W | YFR015C | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | 0.565 |
SGA1 | YGR050C | YIL099W | YGR050C | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.570 |
YGR050C | ELO1 | YGR050C | YJL196C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Elongation of fatty acids protein 1; Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication. | 0.597 |
YGR050C | FRE4 | YGR050C | YNR060W | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Ferric reductase transmembrane component 4; Ferric reductase; reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels. | 0.639 |
YGR050C | GSY1 | YGR050C | YFR015C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | 0.520 |
YGR050C | ICY1 | YGR050C | YMR195W | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | 0.805 |
YGR050C | NDE1 | YGR050C | YMR145C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication. | 0.518 |
YGR050C | PRY3 | YGR050C | YJL078C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p. | 0.755 |
YGR050C | RSB1 | YGR050C | YOR049C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Putative sphingoid long-chain base (LCB) efflux transporter; integral membrane transporter that localizes to the plasma membrane and may transport long chain bases (LCBs) from the cytoplasmic side toward the extracytoplasmic side of the membrane; role in glycerophospholipid translocation; suppressor of the sphingoid LCB sensitivity of an LCB-lyase mutation. | 0.697 |
YGR050C | SGA1 | YGR050C | YIL099W | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | 0.570 |