| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BAP3 | YGR050C | YDR046C | YGR050C | Valine amino-acid permease; Amino acid permease; involved in uptake of cysteine, leucine, isoleucine and valine; BAP3 has a paralog, BAP2, that arose from the whole genome duplication; Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.433 |
| CMD1 | YGR050C | YBR109C | YGR050C | Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.475 |
| ELO1 | YGR050C | YJL196C | YGR050C | Elongation of fatty acids protein 1; Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.535 |
| FRE4 | YGR050C | YNR060W | YGR050C | Ferric reductase transmembrane component 4; Ferric reductase; reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.596 |
| GSY1 | SGA1 | YFR015C | YIL099W | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | 0.647 |
| GSY1 | YGR050C | YFR015C | YGR050C | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.510 |
| ICY1 | YGR050C | YMR195W | YGR050C | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.757 |
| NDE1 | YGR050C | YMR145C | YGR050C | Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.510 |
| PRY3 | YGR050C | YJL078C | YGR050C | Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.703 |
| RSB1 | YGR050C | YOR049C | YGR050C | Putative sphingoid long-chain base (LCB) efflux transporter; integral membrane transporter that localizes to the plasma membrane and may transport long chain bases (LCBs) from the cytoplasmic side toward the extracytoplasmic side of the membrane; role in glycerophospholipid translocation; suppressor of the sphingoid LCB sensitivity of an LCB-lyase mutation. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.651 |
| SGA1 | GSY1 | YIL099W | YFR015C | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | 0.647 |
| SGA1 | YGR050C | YIL099W | YGR050C | Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation. | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | 0.531 |
| YGR050C | BAP3 | YGR050C | YDR046C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Valine amino-acid permease; Amino acid permease; involved in uptake of cysteine, leucine, isoleucine and valine; BAP3 has a paralog, BAP2, that arose from the whole genome duplication; Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family. | 0.433 |
| YGR050C | CMD1 | YGR050C | YBR109C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability. | 0.475 |
| YGR050C | ELO1 | YGR050C | YJL196C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Elongation of fatty acids protein 1; Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication. | 0.535 |
| YGR050C | FRE4 | YGR050C | YNR060W | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Ferric reductase transmembrane component 4; Ferric reductase; reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels. | 0.596 |
| YGR050C | GSY1 | YGR050C | YFR015C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Glycogen [starch] synthase isoform 1; Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; Belongs to the glycosyltransferase 3 family. | 0.510 |
| YGR050C | ICY1 | YGR050C | YMR195W | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Interacting with cytoskeleton protein 1; Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication. | 0.757 |
| YGR050C | NDE1 | YGR050C | YMR145C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Mitochondrial external NADH dehydrogenase; type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain; NDE1 has a paralog, NDE2, that arose from the whole genome duplication. | 0.510 |
| YGR050C | PRY3 | YGR050C | YJL078C | Uncharacterized protein YGR050C; Protein of unknown function; mRNA identified as translated by ribosome profiling data. | Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p. | 0.703 |
