STRINGSTRING
ENV11 protein (Saccharomyces cerevisiae) - STRING interaction network
"ENV11" - Protein proposed to be involved in vacuolar functions in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ENV11Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and fragmented vacuoles; deletion mutant has increased glycogen accumulation and displays elongated buds; green fluorescent protein (GFP)-fusion protein loc /.../ to the nucleus; Involved in vacuolar processing and morphology (860 aa)    
Predicted Functional Partners:
TBF1
Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flan /.../ long T2AG3 repeats and blocks checkpoint activation; Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation of gene expression. 52 binding sites have been identified, distributed over 15 chromosomes. A member of the general regulatory factors (GRFs) which act as genome pa [...] (562 aa)
       
 
  0.925
HTB1
Histone H2B, core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB2; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translat [...] (131 aa)
       
 
  0.790
AFT1
Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability; Probable transcription factor that activates the genes for FRE1, FRE2 and FET3 in response to iron deprivation. Iron could interact directly with AFT1 and inhibits its activity (690 aa)
       
      0.789
VID22
Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles; Has a role in the negative regulation of gluconeogenesis. Imports fructose-1,6-bisphosphatase (FBPase) into the intermediate vacuole import and degradation (Vid) vesicles. This is an indirect role and requires cyclophilin A (901 aa)
       
 
0.758
YPR071W
Putative membrane protein; YPR071W is not an essential gene (211 aa)
           
  0.540
PAU17
Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions; YLL025W is not an essential gene (124 aa)
           
  0.520
YKL023W
Putative protein of unknown function, predicted by computational methods to be involved in mRNA degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm (277 aa)
           
  0.483
IRC10
Protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci (586 aa)
           
  0.440
ABM1
Protein of unknown function, required for normal microtubule organization; Required for normal microtubule organization (123 aa)
           
  0.418
ENV10
Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing; YLR065C is not an essential gene; Involved in vacuolar processing and morphology (181 aa)
           
  0.414
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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