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ECL1 protein (Saccharomyces cerevisiae) - STRING interaction network
"ECL1" - Protein of unknown function, affects chronological lifespan in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ECL1Protein of unknown function, affects chronological lifespan; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation; Involved in chronological cell aging (211 aa)    
Predicted Functional Partners:
DGR1
Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose (48 aa)
           
  0.470
DGR2
Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds (852 aa)
           
  0.469
ICL2
2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol; Catalyzes the formation of pyruvate and succinate from 2-methylisocitrate during the metabolism of endogenous propionyl- CoA. Does not act on isocitrate (575 aa)
           
  0.447
YOL024W
Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site (172 aa)
           
  0.418
YLR030W
Putative protein of unknown function (263 aa)
           
  0.418
YIL024C
Putative protein of unknown function; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p (189 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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