| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HEM1 | MTM1 | YDR232W | YGR257C | 5-aminolevulinate synthase, mitochondrial; 5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5'-phosphate (PLP) transporter, important for delivery of PLP cofactor to mitochondrial enzymes; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential manganese cofactor. | 0.636 |
| HEM1 | YGR237C | YDR232W | YGR237C | 5-aminolevulinate synthase, mitochondrial; 5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.421 |
| IMD4 | YGR237C | YML056C | YGR237C | Inosine-5'-monophosphate dehydrogenase 4; Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in the de novo synthesis of GTP; member of a four-gene family in S. cerevisiae, constitutively expressed; IMD4 has a paralog, IMD3, that arose from the whole genome duplication. | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.469 |
| IMP2 | YGR237C | YIL154C | YGR237C | Sugar utilization regulatory protein IMP2; Transcriptional activator involved in maintenance of ion homeostasis; also involved in protection against DNA damage caused by bleomycin and other oxidants; contains a C-terminal leucine-rich repeat. | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.612 |
| MTM1 | HEM1 | YGR257C | YDR232W | Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5'-phosphate (PLP) transporter, important for delivery of PLP cofactor to mitochondrial enzymes; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential manganese cofactor. | 5-aminolevulinate synthase, mitochondrial; 5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.636 |
| MTM1 | YGR237C | YGR257C | YGR237C | Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5'-phosphate (PLP) transporter, important for delivery of PLP cofactor to mitochondrial enzymes; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential manganese cofactor. | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.834 |
| PSP2 | YGR237C | YML017W | YGR237C | Protein PSP2; Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing. | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.514 |
| YGR237C | HEM1 | YGR237C | YDR232W | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 5-aminolevulinate synthase, mitochondrial; 5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.421 |
| YGR237C | IMD4 | YGR237C | YML056C | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Inosine-5'-monophosphate dehydrogenase 4; Inosine monophosphate dehydrogenase; catalyzes the rate-limiting step in the de novo synthesis of GTP; member of a four-gene family in S. cerevisiae, constitutively expressed; IMD4 has a paralog, IMD3, that arose from the whole genome duplication. | 0.469 |
| YGR237C | IMP2 | YGR237C | YIL154C | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Sugar utilization regulatory protein IMP2; Transcriptional activator involved in maintenance of ion homeostasis; also involved in protection against DNA damage caused by bleomycin and other oxidants; contains a C-terminal leucine-rich repeat. | 0.612 |
| YGR237C | MTM1 | YGR237C | YGR257C | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Mitochondrial protein of the mitochondrial carrier family; high affinity pyridoxal 5'-phosphate (PLP) transporter, important for delivery of PLP cofactor to mitochondrial enzymes; involved in mitochondrial iron homeostasis and in activating mitochondrial Sod2p by facilitating insertion of an essential manganese cofactor. | 0.834 |
| YGR237C | PSP2 | YGR237C | YML017W | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Protein PSP2; Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing. | 0.514 |
| YGR237C | YMR085W | YGR237C | YMR085W | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1. | 0.443 |
| YMR085W | YGR237C | YMR085W | YGR237C | Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1. | Uncharacterized protein YGR237C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.443 |
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