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CPD1 protein (Saccharomyces cerevisiae) - STRING interaction network
"CPD1" - Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CPD1Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1’’, 2’’-cyclic phosphate to ADP-ribose 1’’-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression; Involved in the metabolism of ADP-ribose 1’,2’-cyclic phosphate which is produced as a consequence of tRNA splicing (239 aa)    
Predicted Functional Partners:
TPT1
tRNA 2’-phosphotransferase that catalyzes final step in tRNA splicing- the transfer of the 2’-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1’’-2’’cyclic phosphate and nicotinamide; Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2’-phosphate from ligated tRNA to NAD to produce ADP-ribose 1’’-2’’ cyclic phosphate (230 aa)
         
    0.900
YPR078C
Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible; Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (372 aa)
           
  0.763
SRL4
Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p; May be involved in the regulation of dNTP production. Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (281 aa)
           
  0.742
SDS24
One of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; involved in cell separation during budding; may play an indirect role in fluid-phase endocytosis; Involved in DNA replication and cell separation during budding (527 aa)
           
  0.578
RPN7
Essential non-ATPase regulatory subunit of the 26S proteasome; similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (429 aa)
           
  0.451
SPS4
Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage; Not essential for sporulation. Might be a component of the cell wall (338 aa)
           
  0.418
SPR28
Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation; Septins are GTPases involved in cytokinesis that assemble into filaments and form a ring at the cleavage site. May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation (By similarity) (423 aa)
           
  0.418
EFM4
Probable lysine methyltransferase involved in the dimethylation of eEF1A (Tef1p/Tef2p); sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family; role in vesicular transport; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1- alpha (TEF1 and TEF2) at ’Lys-316’. May play a role in intracellular transport (257 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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