node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CIS3 | CTS1 | YJL158C | YLR286C | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | 0.424 |
CIS3 | EXG1 | YJL158C | YLR300W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Glucan 1,3-beta-glucosidase I/II; Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 5 (cellulase A) family. | 0.608 |
CIS3 | GAS1 | YJL158C | YMR307W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | 1,3-beta-glucanosyltransferase GAS1; Beta-1,3-glucanosyltransferase; required for cell wall assembly and also has a role in transcriptional silencing; localizes to cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate previously unsuspected functions for Gas1 in DNA damage response and cell cycle regulation; Belongs to the glycosyl hydrolase 72 family. | 0.578 |
CIS3 | GAS5 | YJL158C | YOL030W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | 1,3-beta-glucanosyltransferase; has similarity to Gas1p; localizes to the cell wall; Belongs to the glycosyl hydrolase 72 family. | 0.472 |
CIS3 | HSP150 | YJL158C | YJL159W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Cell wall mannoprotein HSP150; O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication. | 0.547 |
CIS3 | SCW10 | YJL158C | YMR305C | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Probable family 17 glucosidase SCW10; Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p; SWC10 has a paralog, SCW4, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 17 family. | 0.812 |
CIS3 | SCW4 | YJL158C | YGR279C | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Probable family 17 glucosidase SCW4; Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 17 family. | 0.853 |
CIS3 | TOS1 | YJL158C | YBR162C | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Protein TOS1; Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C; Belongs to the PGA52 family. | 0.548 |
CTS1 | CIS3 | YLR286C | YJL158C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | 0.424 |
CTS1 | EXG1 | YLR286C | YLR300W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Glucan 1,3-beta-glucosidase I/II; Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 5 (cellulase A) family. | 0.557 |
CTS1 | GAS1 | YLR286C | YMR307W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | 1,3-beta-glucanosyltransferase GAS1; Beta-1,3-glucanosyltransferase; required for cell wall assembly and also has a role in transcriptional silencing; localizes to cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate previously unsuspected functions for Gas1 in DNA damage response and cell cycle regulation; Belongs to the glycosyl hydrolase 72 family. | 0.512 |
CTS1 | HSP150 | YLR286C | YJL159W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Cell wall mannoprotein HSP150; O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication. | 0.455 |
CTS1 | SCW10 | YLR286C | YMR305C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Probable family 17 glucosidase SCW10; Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p; SWC10 has a paralog, SCW4, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 17 family. | 0.779 |
CTS1 | SCW4 | YLR286C | YGR279C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Probable family 17 glucosidase SCW4; Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating; SCW4 has a paralog, SCW10, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 17 family. | 0.777 |
CTS1 | SUN4 | YLR286C | YNL066W | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Probable secreted beta-glucosidase SUN4; Cell wall protein related to glucanases; possibly involved in cell wall septation; member of the SUN family; SUN4 has a paralog, SIM1, that arose from the whole genome duplication. | 0.963 |
CTS1 | TOS1 | YLR286C | YBR162C | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | Protein TOS1; Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C; Belongs to the PGA52 family. | 0.666 |
EXG1 | CIS3 | YLR300W | YJL158C | Glucan 1,3-beta-glucosidase I/II; Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 5 (cellulase A) family. | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | 0.608 |
EXG1 | CTS1 | YLR300W | YLR286C | Glucan 1,3-beta-glucosidase I/II; Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 5 (cellulase A) family. | Endochitinase; required for cell separation after mitosis; transcriptional activation during the G1 phase of the cell cycle is mediated by transcription factor Ace2p. | 0.557 |
EXG1 | GAS1 | YLR300W | YMR307W | Glucan 1,3-beta-glucosidase I/II; Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 5 (cellulase A) family. | 1,3-beta-glucanosyltransferase GAS1; Beta-1,3-glucanosyltransferase; required for cell wall assembly and also has a role in transcriptional silencing; localizes to cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate previously unsuspected functions for Gas1 in DNA damage response and cell cycle regulation; Belongs to the glycosyl hydrolase 72 family. | 0.618 |
EXG1 | GAS5 | YLR300W | YOL030W | Glucan 1,3-beta-glucosidase I/II; Major exo-1,3-beta-glucanase of the cell wall; involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes; EXG1 has a paralog, SPR1, that arose from the whole genome duplication; Belongs to the glycosyl hydrolase 5 (cellulase A) family. | 1,3-beta-glucanosyltransferase; has similarity to Gas1p; localizes to the cell wall; Belongs to the glycosyl hydrolase 72 family. | 0.455 |