node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVL9 | LDB17 | YLR114C | YDL146W | Late secretory pathway protein AVL9; Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; Belongs to the LDB17 family. | 0.449 |
AVL9 | YHL017W | YLR114C | YHL017W | Late secretory pathway protein AVL9; Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress. | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | 0.810 |
CCP1 | YHL017W | YKR066C | YHL017W | Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress. | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | 0.469 |
LDB17 | AVL9 | YDL146W | YLR114C | Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; Belongs to the LDB17 family. | Late secretory pathway protein AVL9; Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.449 |
LDB17 | YAP1802 | YDL146W | YGR241C | Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; Belongs to the LDB17 family. | Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1802 has a paralog, YAP1801, that arose from the whole genome duplication; Belongs to the AP180 family. | 0.476 |
LDB17 | YHL017W | YDL146W | YHL017W | Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; Belongs to the LDB17 family. | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | 0.708 |
SWA2 | YAP1802 | YDR320C | YGR241C | Auxilin-like clathrin uncoating factor SWA2; Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles. | Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1802 has a paralog, YAP1801, that arose from the whole genome duplication; Belongs to the AP180 family. | 0.453 |
SWA2 | YHL017W | YDR320C | YHL017W | Auxilin-like clathrin uncoating factor SWA2; Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles. | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | 0.561 |
YAP1802 | LDB17 | YGR241C | YDL146W | Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1802 has a paralog, YAP1801, that arose from the whole genome duplication; Belongs to the AP180 family. | Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; Belongs to the LDB17 family. | 0.476 |
YAP1802 | SWA2 | YGR241C | YDR320C | Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1802 has a paralog, YAP1801, that arose from the whole genome duplication; Belongs to the AP180 family. | Auxilin-like clathrin uncoating factor SWA2; Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles. | 0.453 |
YAP1802 | YHL017W | YGR241C | YHL017W | Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1802 has a paralog, YAP1801, that arose from the whole genome duplication; Belongs to the AP180 family. | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | 0.553 |
YHL017W | AVL9 | YHL017W | YLR114C | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | Late secretory pathway protein AVL9; Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms; relocalizes from bud neck to cytoplasm upon DNA replication stress. | 0.810 |
YHL017W | CCP1 | YHL017W | YKR066C | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress. | 0.469 |
YHL017W | LDB17 | YHL017W | YDL146W | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | Protein involved in the regulation of endocytosis; transiently recruited to actin cortical patches in a SLA1-dependent manner after late coat component assembly; GFP-fusion protein localizes to the periphery, cytoplasm, bud, and bud neck; Belongs to the LDB17 family. | 0.708 |
YHL017W | SWA2 | YHL017W | YDR320C | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | Auxilin-like clathrin uncoating factor SWA2; Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles. | 0.561 |
YHL017W | YAP1802 | YHL017W | YGR241C | Uncharacterized membrane protein YHL071W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles; YHL017W has a paralog, PTM1, that arose from the whole genome duplication; Belongs to the LU7TM family. | Protein of the AP180 family, involved in clathrin cage assembly; binds Pan1p and clathrin; YAP1802 has a paralog, YAP1801, that arose from the whole genome duplication; Belongs to the AP180 family. | 0.553 |