node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COS8 | YAR069C | YHL048W | YAR069C | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | 0.637 |
COS8 | YAR070C | YHL048W | YAR070C | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Putative uncharacterized protein YAR070C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR070C has a paralog, YHR214C-B, that arose from a segmental duplication. | 0.637 |
COS8 | YHL041W | YHL048W | YHL041W | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Uncharacterized protein YHL041W; Putative protein of unknown function; conserved across S. cerevisiae strains. | 0.698 |
COS8 | YHL044W | YHL048W | YHL044W | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | DUP240 protein YHL044W; Putative integral membrane protein; member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern. | 0.750 |
COS8 | YHL045W | YHL048W | YHL045W | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Putative protein of unknown function; not an essential gene. | 0.805 |
COS8 | YHL046W-A | YHL048W | YHL046W-A | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Putative uncharacterized protein YHL046W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps ORF ARN2/YHL047C. | 0.699 |
COS8 | YHL048C-A | YHL048W | YHL048C-A | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Uncharacterized protein YHL048C-A; Putative protein of unknown function; identified by expression profiling and mass spectrometry. | 0.698 |
COS8 | YHL049C | YHL048W | YHL049C | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Uncharacterized protein YHL049C; Putative protein of unknown function. | 0.764 |
COS8 | YHL050C | YHL048W | YHL050C | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Uncharacterized protein YHL050C; Putative protein of unknown function; potential Cdc28p substrate. | 0.705 |
COS8 | YKL223W | YHL048W | YKL223W | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | Putative UPF0377 protein YKL223W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; Belongs to the UPF0377 family. | 0.696 |
YAR069C | COS8 | YAR069C | YHL048W | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | 0.637 |
YAR069C | YAR070C | YAR069C | YAR070C | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | Putative uncharacterized protein YAR070C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR070C has a paralog, YHR214C-B, that arose from a segmental duplication. | 0.885 |
YAR069C | YHL044W | YAR069C | YHL044W | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | DUP240 protein YHL044W; Putative integral membrane protein; member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern. | 0.754 |
YAR069C | YHL045W | YAR069C | YHL045W | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | Putative protein of unknown function; not an essential gene. | 0.841 |
YAR069C | YHL049C | YAR069C | YHL049C | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | Uncharacterized protein YHL049C; Putative protein of unknown function. | 0.759 |
YAR069C | YHL050C | YAR069C | YHL050C | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | Uncharacterized protein YHL050C; Putative protein of unknown function; potential Cdc28p substrate. | 0.698 |
YAR070C | COS8 | YAR070C | YHL048W | Putative uncharacterized protein YAR070C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR070C has a paralog, YHR214C-B, that arose from a segmental duplication. | Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins; Belongs to the DUP/COS family. | 0.637 |
YAR070C | YAR069C | YAR070C | YAR069C | Putative uncharacterized protein YAR070C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR070C has a paralog, YHR214C-B, that arose from a segmental duplication. | Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication. | 0.885 |
YAR070C | YHL044W | YAR070C | YHL044W | Putative uncharacterized protein YAR070C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR070C has a paralog, YHR214C-B, that arose from a segmental duplication. | DUP240 protein YHL044W; Putative integral membrane protein; member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern. | 0.754 |
YAR070C | YHL045W | YAR070C | YHL045W | Putative uncharacterized protein YAR070C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR070C has a paralog, YHR214C-B, that arose from a segmental duplication. | Putative protein of unknown function; not an essential gene. | 0.838 |