Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
YHL044WDUP240 protein YHL044W; Putative integral membrane protein; member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern. (235 aa)    
Predicted Functional Partners:
YHL045W
Putative protein of unknown function; not an essential gene.
   
  
 0.824
OPI8
Putative uncharacterized protein OPI8; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps verified gene DID2/YKR035W-A.
    
   0.801
YHR218W
Helicase-like protein encoded within the telomeric Y' element.
   
  
 0.778
YHL049C
Uncharacterized protein YHL049C; Putative protein of unknown function.
   
  
 0.755
YHL046W-A
Putative uncharacterized protein YHL046W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps ORF ARN2/YHL047C.
   
  
 0.753
YHL048C-A
Uncharacterized protein YHL048C-A; Putative protein of unknown function; identified by expression profiling and mass spectrometry.
   
  
 0.753
YHL050C
Uncharacterized protein YHL050C; Putative protein of unknown function; potential Cdc28p substrate.
   
  
 0.746
YHL041W
Uncharacterized protein YHL041W; Putative protein of unknown function; conserved across S. cerevisiae strains.
      
 0.745
YHR213W
Putative uncharacterized protein YAR062W; Pseudogenic fragment with similarity to flocculins; YHR213W has a paralog, YAR062W, that arose from a segmental duplication; Belongs to the flocculin family.
      
 0.740
YAR069C
Putative uncharacterized protein YAR069C; Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; YAR069C has a paralog, YHR214C-D, that arose from a segmental duplication.
   
  
 0.714
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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