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COS8 protein (Saccharomyces cerevisiae) - STRING interaction network
"COS8" - Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
COS8Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response (381 aa)    
Predicted Functional Partners:
COS2
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (379 aa)
     
   
0.924
COS4
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (379 aa)
     
   
0.918
COS3
Protein involved in salt resistance; interacts with sodium-hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (379 aa)
     
   
0.916
COS1
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (381 aa)
     
   
0.915
COS7
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (383 aa)
     
   
0.915
COS5
Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (383 aa)
     
   
0.839
YCR061W
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; induced by treatment with 8-methoxypsoralen and UVA irradiation (631 aa)
       
 
  0.681
IRE1
Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices HAC1 precursor mRNA to produce the mature form which then induces transcription of UPR target genes (1115 aa)
       
 
  0.647
YHL050C
Putative protein of unknown function, potential Cdc28p substrate (697 aa)
     
   
  0.643
HIT1
Protein of unknown function, required for growth at high temperature (164 aa)
           
  0.640
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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