Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
YHL050CUncharacterized protein YHL050C; Putative protein of unknown function; potential Cdc28p substrate. (697 aa)    
Predicted Functional Partners:
YHR218W
Helicase-like protein encoded within the telomeric Y' element.
   
  
0.890
YLL067C
Putative Y' element ATP-dependent helicase.
   
  
0.878
YRF1-6
Y' element ATP-dependent helicase protein 1 copy 6; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p.
   
  
0.863
YRF1-5
Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p.
   
  
0.856
YHL045W
Putative protein of unknown function; not an essential gene.
   
  
 0.835
YJR079W
Uncharacterized protein YJR079W; Putative protein of unknown function; mutation results in impaired mitochondrial respiration.
      
 0.830
YRF1-4
Y' element ATP-dependent helicase protein 1 copy 4; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p.
   
  
0.817
YCL012C
UPF0357 protein YCL012C; Protein of unknown function; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; orthologs are present in S. bayanus, S. paradoxus and Ashbya gossypii; YCL012C is not an essential gene; Belongs to the UPF0357 family.
      
 0.811
YHL049C
Uncharacterized protein YHL049C; Putative protein of unknown function.
   
  
 0.785
YLR464W
Putative protein of unknown function; intron is predicted but not detected experimentally; YLR464W overlaps the verified gene YRF1-4/YLR466W and two dubious ORFs YLR463C and YLR465C.
   
    0.757
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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