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ARG4 protein (Saccharomyces cerevisiae) - STRING interaction network
"ARG4" - Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway in Saccharomyces cerevisiae
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Predicted Interactions
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ARG4Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway (463 aa)    
Predicted Functional Partners:
ARG1
Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate; Catalyzes the eighth step in arginine biosynthesis. Also has a catabolic function as the first enzyme of citrulline utilization as nitrogen source via arginine and the reactions involved in the arginase pathway (420 aa)
 
 
  0.999
ARG5,6
Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p (863 aa)
   
 
  0.999
HIS4
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis (799 aa)
   
   
  0.990
CAR1
Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance (333 aa)
         
  0.988
ARG3
Ornithine carbamoyltransferase; also known as carbamoylphosphate-L-ornithine carbamoyltransferase; catalyzes the biosynthesis of the arginine precursor citrulline (338 aa)
   
 
  0.986
ARG7
Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis- the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate (441 aa)
   
   
  0.984
CPA2
Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor (1118 aa)
   
   
  0.952
HIS5
Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts (385 aa)
   
   
  0.950
YGL117W
Putative protein of unknown function (265 aa)
     
   
  0.948
ADE13
Adenylosuccinate lyase, catalyzes two steps in the ’de novo’ purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency (482 aa)
   
 
  0.947
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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