node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE3 | CPS1 | YBR286W | YJL172W | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | 0.785 |
APE3 | DAP2 | YBR286W | YHR028C | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | 0.797 |
APE3 | PRC1 | YBR286W | YMR297W | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family. | 0.631 |
CPS1 | APE3 | YJL172W | YBR286W | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | 0.785 |
CPS1 | DAP2 | YJL172W | YHR028C | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | 0.790 |
CPS1 | PHO8 | YJL172W | YDR481C | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN. | 0.499 |
CPS1 | PRC1 | YJL172W | YMR297W | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family. | 0.896 |
DAP2 | APE3 | YHR028C | YBR286W | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Vacuolar aminopeptidase Y; processed to mature form by Prb1p. | 0.797 |
DAP2 | CPS1 | YHR028C | YJL172W | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | 0.790 |
DAP2 | PHO8 | YHR028C | YDR481C | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN. | 0.814 |
DAP2 | PRC1 | YHR028C | YMR297W | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family. | 0.861 |
DAP2 | SBH1 | YHR028C | YER087C-B | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Protein transport protein SBH1; Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; interacts with the exocyst complex and also with Rtn1p; cotranslationally N-acetylated by NatA; SBH1 has a paralog, SBH2, that arose from the whole genome duplication; Belongs to the SEC61-beta family. | 0.780 |
DAP2 | SBH2 | YHR028C | YER019C-A | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Ssh1p-Sss1p-Sbh2p complex component; involved in protein translocation into the endoplasmic reticulum; SBH2 has a paralog, SBH1, that arose from the whole genome duplication; Belongs to the SEC61-beta family. | 0.724 |
DAP2 | SEC61 | YHR028C | YLR378C | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Conserved ER protein translocation channel; essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms channel for SRP-dependent protein import; with Sec63 complex allows SRP-independent protein import into ER; involved in posttranslational soluble protein import into the ER, ERAD of soluble substrates, and misfolded soluble protein export from the ER. | 0.832 |
DAP2 | SEC62 | YHR028C | YPL094C | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Translocation protein SEC62; Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; cotranslationally N-acetylated by NatA; other members are Sec63p, Sec66p, and Sec72p. | 0.793 |
DAP2 | SEC65 | YHR028C | YML105C | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Subunit of the signal recognition particle (SRP); involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19. | 0.792 |
DAP2 | SRP54 | YHR028C | YPR088C | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain. | 0.713 |
PHO8 | CPS1 | YDR481C | YJL172W | Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN. | Vacuolar carboxypeptidase S; expression is induced under low-nitrogen conditions. | 0.499 |
PHO8 | DAP2 | YDR481C | YHR028C | Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN. | Dipeptidyl aminopeptidase; synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p. | 0.814 |
PHO8 | PRC1 | YDR481C | YMR297W | Repressible vacuolar alkaline phosphatase; regulated by levels of Pi and by Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides; contributes to NAD+ metabolism by producing nicotinamide riboside from NMN. | Vacuolar carboxypeptidase Y (proteinase C, CPY); broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family. | 0.849 |