node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCD1 | HIT1 | YHR040W | YJR055W | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | 0.756 |
BCD1 | NAF1 | YHR040W | YNL124W | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p; Belongs to the NAF1 family. | 0.780 |
BCD1 | NOP58 | YHR040W | YOR310C | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | Nucleolar protein 58; Protein involved in producing mature rRNAs and snoRNAs; involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA. | 0.897 |
BCD1 | PIH1 | YHR040W | YHR034C | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | Protein interacting with Hsp90 1; Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly large protein complexes such as box C/D snoRNPs and RNA polymerase II. | 0.812 |
BCD1 | POP4 | YHR040W | YBR257W | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | RNases MRP/P 32.9 kDa subunit; Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P. | 0.809 |
BCD1 | RTT106 | YHR040W | YNL206C | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | Histone chaperone; involved in regulation of chromatin structure in both transcribed and silenced chromosomal regions; affects transcriptional elongation; has a role in regulation of Ty1 transposition; interacts physically and functionally with Chromatin Assembly Factor-1 (CAF-1); Belongs to the RTT106 family. | 0.959 |
BCD1 | RVB1 | YHR040W | YDR190C | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | RuvB-like protein 1; ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.726 |
BCD1 | RVB2 | YHR040W | YPL235W | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | RuvB-like protein 2; ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.806 |
BCD1 | SNU13 | YHR040W | YEL026W | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | 13 kDa ribonucleoprotein-associated protein; RNA binding protein; part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.739 |
BCD1 | TAH1 | YHR040W | YCR060W | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | TPR repeat-containing protein associated with Hsp90; Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly of large protein complexes such as box C/D snoRNPs and RNA polymerase II; contains a single TPR domain with at least two TPR motifs; plays a role in determining prion variants. | 0.767 |
HIT1 | BCD1 | YJR055W | YHR040W | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | 0.756 |
HIT1 | NOP58 | YJR055W | YOR310C | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | Nucleolar protein 58; Protein involved in producing mature rRNAs and snoRNAs; involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA. | 0.567 |
HIT1 | PIH1 | YJR055W | YHR034C | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | Protein interacting with Hsp90 1; Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly large protein complexes such as box C/D snoRNPs and RNA polymerase II. | 0.520 |
HIT1 | RVB1 | YJR055W | YDR190C | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | RuvB-like protein 1; ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.431 |
HIT1 | RVB2 | YJR055W | YPL235W | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | RuvB-like protein 2; ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly. | 0.403 |
HIT1 | SNU13 | YJR055W | YEL026W | Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; similar to human ZNHIT3. | 13 kDa ribonucleoprotein-associated protein; RNA binding protein; part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.637 |
NAF1 | BCD1 | YNL124W | YHR040W | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p; Belongs to the NAF1 family. | Box C/D snoRNA protein 1; Essential protein required for the accumulation of box C/D snoRNA. | 0.780 |
NAF1 | NOP58 | YNL124W | YOR310C | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p; Belongs to the NAF1 family. | Nucleolar protein 58; Protein involved in producing mature rRNAs and snoRNAs; involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA. | 0.819 |
NAF1 | POP4 | YNL124W | YBR257W | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p; Belongs to the NAF1 family. | RNases MRP/P 32.9 kDa subunit; Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P. | 0.704 |
NAF1 | SNU13 | YNL124W | YEL026W | H/ACA ribonucleoprotein complex non-core subunit NAF1; RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p; Belongs to the NAF1 family. | 13 kDa ribonucleoprotein-associated protein; RNA binding protein; part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein; Belongs to the eukaryotic ribosomal protein eL8 family. | 0.741 |