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LAM4 protein (Saccharomyces cerevisiae) - STRING interaction network
"LAM4" - Protein of unknown function that may interact with ribosomes, based on co-purification experiments in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LAM4Protein of unknown function that may interact with ribosomes, based on co-purification experiments; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; May be involved in sterol transfer between intracellular membranes (1345 aa)    
Predicted Functional Partners:
MRPS12
Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins; Required for respiratory growth (153 aa)
           
  0.680
SHE10
Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest; Involved in spore wall assembly (PubMed-23966878). May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed-20086051). Causes growth arrest when highly overexpressed (PubMed-7762298) (577 aa)
           
  0.544
PET117
Protein required for assembly of cytochrome c oxidase; Involved in the assembly of cytochrome c oxidase (107 aa)
           
  0.485
OSW7
Putative protein of unknown function; may be involved in response to high salt and changes in carbon source; deletion mutant has decreased spore survival in Drosophila feces; Involved in spore wall assembly (510 aa)
           
  0.483
LAM1
Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone; Involved in mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone (PubMed-15657396, PubMed-18800175). May be involved in sterol transfer between intracellular membranes (PubMed-26001273) (1228 aa)
     
   
  0.478
IMA2
Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose; member of IMA isomaltase family; not required for isomaltose utilization, but Ima2p overexpression allows the ima1 null mutant to grow on isomaltose; Alpha-glucosidase with specificity for isomaltase, methyl-alpha-glucoside, and palatinose (589 aa)
       
      0.475
IMA4
Alpha-glucosidase with broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima4p overexpression allows the ima1 null mutant to grow on isomaltose; Alpha-glucosidase with broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides. Not required for isomaltose utilization, but overexpression allows the IMA1 null mutant to grow on isomaltose (589 aa)
       
      0.475
IMA5
Alpha-glucosidase with specificity for isomaltose, maltose, and palatinose; member of the IMA isomaltase family; not required for isomaltose utilization, but Ima5p overexpression allows the ima1 null mutant to grow on isomaltose; Alpha-glucosidase with specificity for isomaltose, maltose, and palatinose (581 aa)
       
      0.475
IMA3
Alpha-glucosidase with broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima3p overexpression allows the ima1 null mutant to grow on isomaltose (589 aa)
       
      0.475
MAL12
Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus; hydrolyzes the disaccharides maltose, turanose, maltotriose, and sucrose (584 aa)
       
      0.475
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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