node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IMG1 | MRM2 | YCR046C | YGL136C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | 0.775 |
IMG1 | MRP7 | YCR046C | YNL005C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG1 | MRPL19 | YCR046C | YNL185C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.996 |
IMG1 | MRPL32 | YCR046C | YCR003W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 0.999 |
IMG1 | MRPL39 | YCR046C | YML009C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG1 | MRPL8 | YCR046C | YJL063C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG1 | MTG1 | YCR046C | YMR097C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial GTPase 1; Putative GTPase peripheral to the mitochondrial inner membrane; essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals. | 0.750 |
IMG1 | MTG2 | YCR046C | YHR168W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | GTPase MTG2, mitochondrial; Putative GTPase; member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.940 |
IMG1 | RTC6 | YCR046C | YPL183W-A | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | 54S ribosomal protein RTC6, mitochondrial; Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress; Belongs to the bacterial ribosomal protein bL36 family. | 0.999 |
MRM2 | IMG1 | YGL136C | YCR046C | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | 0.775 |
MRM2 | MRP7 | YGL136C | YNL005C | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial ribosomal protein of the large subunit. | 0.698 |
MRM2 | MRPL19 | YGL136C | YNL185C | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial ribosomal protein of the large subunit. | 0.764 |
MRM2 | MRPL32 | YGL136C | YCR003W | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 0.663 |
MRM2 | MRPL39 | YGL136C | YML009C | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial ribosomal protein of the large subunit. | 0.670 |
MRM2 | MRPL8 | YGL136C | YJL063C | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial ribosomal protein of the large subunit. | 0.613 |
MRM2 | MTG1 | YGL136C | YMR097C | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Mitochondrial GTPase 1; Putative GTPase peripheral to the mitochondrial inner membrane; essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals. | 0.949 |
MRM2 | MTG2 | YGL136C | YHR168W | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | GTPase MTG2, mitochondrial; Putative GTPase; member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.946 |
MRM2 | RTC6 | YGL136C | YPL183W-A | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | 54S ribosomal protein RTC6, mitochondrial; Protein involved in translation; mutants have defects in biogenesis of nuclear ribosomes; sequence similar to prokaryotic ribosomal protein L36, may be a mitochondrial ribosomal protein; protein abundance increases in response to DNA replication stress; Belongs to the bacterial ribosomal protein bL36 family. | 0.922 |
MRP7 | IMG1 | YNL005C | YCR046C | Mitochondrial ribosomal protein of the large subunit. | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | 0.999 |
MRP7 | MRM2 | YNL005C | YGL136C | Mitochondrial ribosomal protein of the large subunit. | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | 0.698 |