Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CRG1 | KDX1 | YHR209W | YKL161C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | 0.665 |
| CRG1 | NAR1 | YHR209W | YNL240C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Cytosolic Fe-S cluster assembly factor NAR1; Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery; required for maturation of cytosolic and nuclear FeS proteins and for normal resistance to oxidative stress; deficiency results in shortened lifespan and sensitivity to paraquat; homologous to human Narf. | 0.647 |
| CRG1 | NCW2 | YHR209W | YLR194C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | 0.611 |
| CRG1 | PER1 | YHR209W | YCR044C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Protein of the endoplasmic reticulum; required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1. | 0.524 |
| CRG1 | PRM5 | YHR209W | YIL117C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | 0.604 |
| CRG1 | SLT2 | YHR209W | YHR030C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Mitogen-activated protein kinase SLT2/MPK1; Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kin [...] | 0.641 |
| CRG1 | SRL3 | YHR209W | YKR091W | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Protein SRL3; GTB motif (G1/S transcription factor binding) containing protein; binds SBF-regulated promoters in hydroxyurea-treated cells; when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate; SRL3 has a paralog, WHI5, that arose from the whole genome duplication. | 0.778 |
| CRG1 | TRM112 | YHR209W | YNR046W | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Multifunctional methyltransferase subunit TRM112; Protein involved in methylation of tRNA, rRNA, and translation factors; also involved in ribosome biogenesis; subunit of tRNA methyltransferase (MTase) complexes in combination with Trm9p and Trm11p; N7-methylates G1575 of 18S rRNA as complex with Bud23p; subunit of complex with Mtq2p that methylates Sup45p (eRF1) in the ternary complex eRF1-eRF3-GTP; relative distribution to the nucleus increases upon DNA replication stress; functional homolog of human TRMT112. | 0.582 |
| CRG1 | YNR065C | YHR209W | YNR065C | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Uncharacterized membrane glycoprotein YNR065C; Protein of unknown function; protein-protein interactions suggest a possible role in actin patch formation; YNR065C is not an essential gene. | 0.538 |
| CRG1 | YPL088W | YHR209W | YPL088W | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | Putative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. | 0.564 |
| KDX1 | CRG1 | YKL161C | YHR209W | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | 0.665 |
| KDX1 | NCW2 | YKL161C | YLR194C | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | 0.529 |
| KDX1 | PRM5 | YKL161C | YIL117C | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | 0.639 |
| KDX1 | SLT2 | YKL161C | YHR030C | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | Mitogen-activated protein kinase SLT2/MPK1; Serine/threonine MAP kinase; coordinates expression of all 19S regulatory particle assembly-chaperones (RACs) to control proteasome abundance; involved in regulating maintenance of cell wall integrity, cell cycle progression, nuclear mRNA retention in heat shock, septum assembly; required for mitophagy, pexophagy; affects recruitment of mitochondria to phagophore assembly site; plays role in adaptive response of cells to cold; regulated by the PKC1-mediated signaling pathway; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kin [...] | 0.689 |
| KDX1 | SRL3 | YKL161C | YKR091W | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | Protein SRL3; GTB motif (G1/S transcription factor binding) containing protein; binds SBF-regulated promoters in hydroxyurea-treated cells; when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate; SRL3 has a paralog, WHI5, that arose from the whole genome duplication. | 0.605 |
| KDX1 | YNR065C | YKL161C | YNR065C | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | Uncharacterized membrane glycoprotein YNR065C; Protein of unknown function; protein-protein interactions suggest a possible role in actin patch formation; YNR065C is not an essential gene. | 0.552 |
| NAR1 | CRG1 | YNL240C | YHR209W | Cytosolic Fe-S cluster assembly factor NAR1; Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery; required for maturation of cytosolic and nuclear FeS proteins and for normal resistance to oxidative stress; deficiency results in shortened lifespan and sensitivity to paraquat; homologous to human Narf. | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | 0.647 |
| NCW2 | CRG1 | YLR194C | YHR209W | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | Probable S-adenosylmethionine-dependent methyltransferase CRG1; S-AdoMet-dependent methyltransferase involved in lipid homeostasis; mediates resistance to a drug cantharidin; Belongs to the methyltransferase superfamily. | 0.611 |
| NCW2 | KDX1 | YLR194C | YKL161C | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | Serine/threonine-protein kinase KDX1; Protein kinase; implicated in Slt2p mitogen-activated (MAP) kinase signaling pathway; interacts with numerous components in the mating pheromone and CWI MAPK pathways; associates with Rlm1p; KDX1 has a paralog, SLT2, that arose from the whole genome duplication. | 0.529 |
| NCW2 | PRM5 | YLR194C | YIL117C | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication. | 0.661 |
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