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PRM2 protein (Saccharomyces cerevisiae) - STRING interaction network
"PRM2" - Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PRM2Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion (656 aa)    
Predicted Functional Partners:
FIG1
Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating; Required for efficient mating (298 aa)
     
   
  0.525
FUS2
Cytoplasmic protein localized to the shmoo tip; required for the alignment of parental nuclei before nuclear fusion during mating; Promotes cell fusion during zygote formation (677 aa)
     
   
  0.519
PRM1
Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event (661 aa)
     
   
  0.514
YOR072W
Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive (104 aa)
           
  0.482
ZRG8
Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency; Involved in the integrity functions of RAM, a conserved signaling network that regulates maintenance of polarized growth and daughter-cell-specific transcription (1076 aa)
           
  0.480
YSY6
Protein whose expression suppresses a secretory pathway mutation in E. coli; has similarity to the mammalian RAMP4 protein involved in secretion; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential) (65 aa)
           
  0.469
YMR031W-A
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays shortened telomeres; partially overlaps the uncharacterized ORF YMR031C (108 aa)
           
  0.418
YKL077W
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole (392 aa)
           
  0.418
YHL045W
Putative protein of unknown function; not an essential gene (115 aa)
           
  0.418
PET117
Protein required for assembly of cytochrome c oxidase; Involved in the assembly of cytochrome c oxidase (107 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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