| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGA2 | YIL152W | YGL032C | YIL152W | Adhesion subunit of a-agglutinin of a-cells; C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.604 |
| AIM32 | YIL152W | YML050W | YIL152W | Altered inheritance of mitochondria protein 32; Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.652 |
| EGO4 | YIL152W | YNR034W-A | YIL152W | Uncharacterized protein YNR034W-A; Protein of unknown function; expression is regulated by Msn2p/Msn4p; YNR034W-A has a paralog, YCR075W-A, that arose from the whole genome duplication. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.657 |
| FAR7 | LCL2 | YFR008W | YLR104W | Factor arrest protein 7; Protein involved in recovery from pheromone-induced cell cycle arrest; acts in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p; protein abundance increases in response to DNA replication stress. | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | 0.449 |
| FAR7 | YIL152W | YFR008W | YIL152W | Factor arrest protein 7; Protein involved in recovery from pheromone-induced cell cycle arrest; acts in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p; protein abundance increases in response to DNA replication stress. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.595 |
| GIR2 | YIL152W | YDR152W | YIL152W | Protein GIR2; Highly-acidic RWD domain-containing cytoplasmic protein; forms a highly conserved complex with Rbg2p that is responsible for efficient cell growth under amino acid starvation and binds translational activator Gcn1p in dose-dependent manner according to stress level; associates with translating ribosomes; intrinsically unstructured protein whose stability is enhanced upon binding Rbg2p; Belongs to the RWDD1/GIR2 family. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.657 |
| LCL2 | FAR7 | YLR104W | YFR008W | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | Factor arrest protein 7; Protein involved in recovery from pheromone-induced cell cycle arrest; acts in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p; protein abundance increases in response to DNA replication stress. | 0.449 |
| LCL2 | NDL1 | YLR104W | YLR254C | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | Homolog of nuclear distribution factor NudE; NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends. | 0.510 |
| LCL2 | YDL012C | YLR104W | YDL012C | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | Cysteine-rich and transmembrane domain-containing protein YDL012C; Tail-anchored plasma membrane protein with a conserved CYSTM module; possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype; YDL012C has a paralog, YBR016W, that arose from the whole genome duplication; Belongs to the CYSTM1 family. | 0.539 |
| LCL2 | YIL152W | YLR104W | YIL152W | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.747 |
| NDL1 | LCL2 | YLR254C | YLR104W | Homolog of nuclear distribution factor NudE; NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends. | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | 0.510 |
| NDL1 | YIL152W | YLR254C | YIL152W | Homolog of nuclear distribution factor NudE; NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.684 |
| SHU2 | YIL152W | YDR078C | YIL152W | Suppressor of hydroxyurea sensitivity protein 2; Component of Shu complex (aka PCSS complex); Shu complex also includes Psy3, Csm2, Shu1, and promotes error-free DNA repair, Shu complex mediates inhibition of Srs2p function; promotes formation of Rad51p filaments; important for both mitotic and meiotic homologous recombination, and contains a conserved SWIM domain that is necessary for both. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.843 |
| TDA2 | YIL152W | YER071C | YIL152W | Topoisomerase I damage affected protein 2; Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; null mutant is sensitive to expression of the top1-T722A allele. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.635 |
| YDL012C | LCL2 | YDL012C | YLR104W | Cysteine-rich and transmembrane domain-containing protein YDL012C; Tail-anchored plasma membrane protein with a conserved CYSTM module; possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype; YDL012C has a paralog, YBR016W, that arose from the whole genome duplication; Belongs to the CYSTM1 family. | Long chronological lifespan protein 2; Putative protein of unknown function; mutant is deficient in cell wall mannosylphosphate and has long chronological lifespan; genetic interactions suggest a role in ER-associated protein degradation (ERAD); SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, while mCherry fusion localizes to just the vacuole. | 0.539 |
| YDL012C | YIL152W | YDL012C | YIL152W | Cysteine-rich and transmembrane domain-containing protein YDL012C; Tail-anchored plasma membrane protein with a conserved CYSTM module; possibly involved in response to stress; may contribute to non-homologous end-joining (NHEJ) based on ydl012c htz1 double null phenotype; YDL012C has a paralog, YBR016W, that arose from the whole genome duplication; Belongs to the CYSTM1 family. | Uncharacterized protein YIL152W; Putative protein of unknown function. | 0.677 |
| YIL152W | AGA2 | YIL152W | YGL032C | Uncharacterized protein YIL152W; Putative protein of unknown function. | Adhesion subunit of a-agglutinin of a-cells; C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds. | 0.604 |
| YIL152W | AIM32 | YIL152W | YML050W | Uncharacterized protein YIL152W; Putative protein of unknown function. | Altered inheritance of mitochondria protein 32; Protein of unknown function; null mutant is viable and displays elevated frequency of mitochondrial genome loss. | 0.652 |
| YIL152W | EGO4 | YIL152W | YNR034W-A | Uncharacterized protein YIL152W; Putative protein of unknown function. | Uncharacterized protein YNR034W-A; Protein of unknown function; expression is regulated by Msn2p/Msn4p; YNR034W-A has a paralog, YCR075W-A, that arose from the whole genome duplication. | 0.657 |
| YIL152W | FAR7 | YIL152W | YFR008W | Uncharacterized protein YIL152W; Putative protein of unknown function. | Factor arrest protein 7; Protein involved in recovery from pheromone-induced cell cycle arrest; acts in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p; protein abundance increases in response to DNA replication stress. | 0.595 |
