STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YIL165CPutative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. (119 aa)    
Predicted Functional Partners:
NIT1
Putative nitrilase-like protein NIT1; Nitrilase; member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
 
  
 0.999
YGR111W
Uncharacterized protein YGR111W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus.
     
 0.798
YOR376W-A
Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR.
      
 0.793
YOR012W
Uncharacterized protein YOR012W; Putative protein of unknown function.
      
 0.792
YDR133C
Putative uncharacterized protein YDR133C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps YDR134C.
   
  
 0.760
YGR127W
Uncharacterized protein YGR127W; Putative protein of unknown function; expression is regulated by Msn2p/Msn4p, indicating a possible role in stress response.
      
 0.697
YMR085W
Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains, and together are paralogous to glutamine-fructose-6-phosphate amidotransferase GFA1.
  
  
 0.674
CMR2
Uncharacterized protein YOR093C; Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-inducing agents.
    
 
 0.655
DUR1,2
Allophanate hydrolase; Urea amidolyase; contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation; protein abundance increases in response to DNA replication stress.
  
 0.623
UGA1
4-aminobutyrate aminotransferase; Gamma-aminobutyrate (GABA) transaminase; also known as 4-aminobutyrate aminotransferase; involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization; protein abundance increases in response to DNA replication stress; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.608
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.