node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COX16 | RPL25 | YJL003W | YOL127W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | 0.948 |
COX16 | RPL32 | YJL003W | YBL092W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Ribosomal 60S subunit protein L32; overexpression disrupts telomeric silencing; homologous to mammalian ribosomal protein L32, no bacterial homolog. | 0.947 |
COX16 | RPL38 | YJL003W | YLR325C | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Ribosomal 60S subunit protein L38; homologous to mammalian ribosomal protein L38, no bacterial homolog; Belongs to the eukaryotic ribosomal protein eL38 family. | 0.943 |
COX16 | RPL39 | YJL003W | YJL189W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Ribosomal 60S subunit protein L39; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1; homologous to mammalian ribosomal protein L39, no bacterial homolog. | 0.942 |
COX16 | RPL5 | YJL003W | YPL131W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly; Belongs to the universal ribosomal protein uL18 family. | 0.946 |
COX16 | RPS13 | YJL003W | YDR064W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S13 and bacterial S15. | 0.941 |
COX16 | RPS15 | YJL003W | YOL040C | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15 and bacterial S19. | 0.948 |
COX16 | RPS20 | YJL003W | YHL015W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; homologous to mammalian ribosomal protein S20 and bacterial S10. | 0.942 |
COX16 | RPS21B | YJL003W | YJL136C | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S21, no bacterial homolog; RPS21B has a paralog, RPS21A, that arose from the whole genome duplication. | 0.940 |
COX16 | RPS3 | YJL003W | YNL178W | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3. | 0.946 |
RPL25 | COX16 | YOL127W | YJL003W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase. | 0.948 |
RPL25 | RPL32 | YOL127W | YBL092W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Ribosomal 60S subunit protein L32; overexpression disrupts telomeric silencing; homologous to mammalian ribosomal protein L32, no bacterial homolog. | 0.999 |
RPL25 | RPL38 | YOL127W | YLR325C | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Ribosomal 60S subunit protein L38; homologous to mammalian ribosomal protein L38, no bacterial homolog; Belongs to the eukaryotic ribosomal protein eL38 family. | 0.999 |
RPL25 | RPL39 | YOL127W | YJL189W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Ribosomal 60S subunit protein L39; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1; homologous to mammalian ribosomal protein L39, no bacterial homolog. | 0.999 |
RPL25 | RPL5 | YOL127W | YPL131W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly; Belongs to the universal ribosomal protein uL18 family. | 0.999 |
RPL25 | RPS13 | YOL127W | YDR064W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S13 and bacterial S15. | 0.999 |
RPL25 | RPS15 | YOL127W | YOL040C | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15 and bacterial S19. | 0.999 |
RPL25 | RPS20 | YOL127W | YHL015W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; homologous to mammalian ribosomal protein S20 and bacterial S10. | 0.999 |
RPL25 | RPS21B | YOL127W | YJL136C | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S21, no bacterial homolog; RPS21B has a paralog, RPS21A, that arose from the whole genome duplication. | 0.999 |
RPL25 | RPS3 | YOL127W | YNL178W | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3. | 0.999 |