node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACT1 | CCT2 | YFL039C | YIL142W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.866 |
ACT1 | CCT3 | YFL039C | YJL014W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit gamma; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; capable of binding Q/N rich proteins and mediating their folding. | 0.884 |
ACT1 | CCT4 | YFL039C | YDL143W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit delta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.866 |
ACT1 | CCT5 | YFL039C | YJR064W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit epsilon; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.892 |
ACT1 | CCT6 | YFL039C | YDR188W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit zeta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif. | 0.823 |
ACT1 | CCT7 | YFL039C | YJL111W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit eta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; mutant has increased aneuploidy tolerance. | 0.908 |
ACT1 | CCT8 | YFL039C | YJL008C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | T-complex protein 1 subunit theta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.883 |
ACT1 | PAC10 | YFL039C | YGR078C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Prefoldin subunit 3; Part of the heteromeric co-chaperone GimC/prefoldin complex; complex promotes efficient protein folding; Belongs to the prefoldin subunit alpha family. | 0.704 |
ACT1 | PLP2 | YFL039C | YOR281C | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Phosducin-like protein 2; Protein that interacts with the CCT complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP; CCT is short for chaperonin containing TCP-1; essential gene. | 0.620 |
ACT1 | TCP1 | YFL039C | YDR212W | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | Alpha subunit of chaperonin-containing T-complex; complex mediates protein folding in the cytosol; involved in actin cytoskeleton maintenance; overexpression in neurons suppresses formation of pathogenic conformations of huntingtin protein. | 0.950 |
CCT2 | ACT1 | YIL142W | YFL039C | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | Actin; structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions. | 0.866 |
CCT2 | CCT3 | YIL142W | YJL014W | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | T-complex protein 1 subunit gamma; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; capable of binding Q/N rich proteins and mediating their folding. | 0.999 |
CCT2 | CCT4 | YIL142W | YDL143W | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | T-complex protein 1 subunit delta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.999 |
CCT2 | CCT5 | YIL142W | YJR064W | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | T-complex protein 1 subunit epsilon; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.999 |
CCT2 | CCT6 | YIL142W | YDR188W | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | T-complex protein 1 subunit zeta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif. | 0.999 |
CCT2 | CCT7 | YIL142W | YJL111W | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | T-complex protein 1 subunit eta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; mutant has increased aneuploidy tolerance. | 0.999 |
CCT2 | CCT8 | YIL142W | YJL008C | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | T-complex protein 1 subunit theta; Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | 0.999 |
CCT2 | PAC10 | YIL142W | YGR078C | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | Prefoldin subunit 3; Part of the heteromeric co-chaperone GimC/prefoldin complex; complex promotes efficient protein folding; Belongs to the prefoldin subunit alpha family. | 0.887 |
CCT2 | PLP2 | YIL142W | YOR281C | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | Phosducin-like protein 2; Protein that interacts with the CCT complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP; CCT is short for chaperonin containing TCP-1; essential gene. | 0.971 |
CCT2 | TCP1 | YIL142W | YDR212W | T-complex protein 1 subunit beta; Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo. | Alpha subunit of chaperonin-containing T-complex; complex mediates protein folding in the cytosol; involved in actin cytoskeleton maintenance; overexpression in neurons suppresses formation of pathogenic conformations of huntingtin protein. | 0.999 |