node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAC3 | BIL1 | YBR085W | YOR304C-A | Solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31; ADP,ATP carrier protein 3; Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication; Belongs to the mitochondrial carrier (TC 2.A.29) family | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | 0.485 |
AAC3 | PET130 | YBR085W | YJL023C | Solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31; ADP,ATP carrier protein 3; Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication; Belongs to the mitochondrial carrier (TC 2.A.29) family | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | 0.693 |
AAC3 | RPP1B | YBR085W | YDL130W | Solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31; ADP,ATP carrier protein 3; Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication; Belongs to the mitochondrial carrier (TC 2.A.29) family | 60S acidic ribosomal protein P1-beta; Ribosomal protein P1 beta; component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; free (non-ribosomal) P1 stimulates the phosphorylation of the eIF2 alpha subunit (Sui2p) by Gcn2p; accumulation is regulated by phosphorylation and interaction with the P2 stalk component | 0.414 |
BIL1 | AAC3 | YOR304C-A | YBR085W | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | Solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31; ADP,ATP carrier protein 3; Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.485 |
BIL1 | CBS1 | YOR304C-A | YDL069C | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | Cytochrome b translational activator protein cbs1, mitochondrial; Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader | 0.577 |
BIL1 | PET130 | YOR304C-A | YJL023C | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | 0.813 |
BIL1 | RPP1B | YOR304C-A | YDL130W | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | 60S acidic ribosomal protein P1-beta; Ribosomal protein P1 beta; component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; free (non-ribosomal) P1 stimulates the phosphorylation of the eIF2 alpha subunit (Sui2p) by Gcn2p; accumulation is regulated by phosphorylation and interaction with the P2 stalk component | 0.566 |
BIL1 | RPP2B | YOR304C-A | YDR382W | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | 60S acidic ribosomal protein P2-beta; Ribosomal protein P2 beta; a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; free (non-ribosomal) P2 stimulates the phosphorylation of the eIF2 alpha subunit (Sui2p) by Gcn2p; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm | 0.454 |
CBS1 | BIL1 | YDL069C | YOR304C-A | Cytochrome b translational activator protein cbs1, mitochondrial; Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | 0.577 |
CBS1 | PET130 | YDL069C | YJL023C | Cytochrome b translational activator protein cbs1, mitochondrial; Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | 0.716 |
GEP5 | IRC19 | YLR091W | YLL033W | Genetic interactor of prohibitin 5, mitochondrial; Protein of unknown function; required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine | Increased recombination centers protein 19; Protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci | 0.773 |
GEP5 | PET130 | YLR091W | YJL023C | Genetic interactor of prohibitin 5, mitochondrial; Protein of unknown function; required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | 0.920 |
GEP5 | RPM2 | YLR091W | YML091C | Genetic interactor of prohibitin 5, mitochondrial; Protein of unknown function; required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine | Protein subunit of mitochondrial RNase P; has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus | 0.713 |
GEP5 | RRG8 | YLR091W | YPR116W | Genetic interactor of prohibitin 5, mitochondrial; Protein of unknown function; required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine | Protein of unknown function; required for mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport; Belongs to the RRG8 family | 0.948 |
IRC19 | GEP5 | YLL033W | YLR091W | Increased recombination centers protein 19; Protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci | Genetic interactor of prohibitin 5, mitochondrial; Protein of unknown function; required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine | 0.773 |
IRC19 | PET130 | YLL033W | YJL023C | Increased recombination centers protein 19; Protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | 0.823 |
IRC19 | RRG8 | YLL033W | YPR116W | Increased recombination centers protein 19; Protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci | Protein of unknown function; required for mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport; Belongs to the RRG8 family | 0.868 |
IRC19 | YPR117W | YLL033W | YPR117W | Increased recombination centers protein 19; Protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci | Uncharacterized protein YPR117W; Putative protein of unknown function | 0.892 |
PET130 | AAC3 | YJL023C | YBR085W | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | Solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31; ADP,ATP carrier protein 3; Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.693 |
PET130 | BIL1 | YJL023C | YOR304C-A | Protein pet130; Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies | Uncharacterized protein YOR304C-A; Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | 0.813 |