STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL8Mitochondrial 54s ribosomal protein yml8; Mitochondrial ribosomal protein of the large subunit (238 aa)    
Predicted Functional Partners:
MRPL16
Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation
  
 
 0.999
MRPS9
Mitochondrial 37s ribosomal protein mrps9; Mitochondrial ribosomal protein of the small subunit
  
 
 0.999
MRPS5
Mitochondrial 37s ribosomal protein mrps5; Mitochondrial ribosomal protein of the small subunit
  
 
 0.999
MRPL27
Mitochondrial 54s ribosomal protein yml27; Mitochondrial ribosomal protein of the large subunit; homolog of human Bcl-2 interacting protein BMRP
   
   0.999
MRPL32
Mitochondrial 54s ribosomal protein yml32; Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress
  
 
 0.999
IMG1
54S ribosomal protein IMG1, mitochondrial; Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome
  
 
 0.999
MRPS28
Mitochondrial 37s ribosomal protein mrps28; Mitochondrial ribosomal protein of the small subunit
  
 
 0.999
MRP20
Mitochondrial 54s ribosomal protein yml41; Mitochondrial ribosomal protein of the large subunit
   
   0.999
MRPL28
Mitochondrial 54s ribosomal protein yml28; Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress
   
 
 0.999
RML2
Mitochondrial ribosomal protein of the large subunit (L2); has similarity to E. coli L2 ribosomal protein; mutant allele (fat21) causes inability to utilize oleate, and induce oleic acid oxidation; may interfere with activity of the Adr1p transcription factor
 
 
 0.999
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.