PRY3 protein (Saccharomyces cerevisiae) - STRING interaction network
"PRY3" - Cell wall protein with a role in mating efficiency in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
PRY3Cell wall protein with a role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p; Isoform Long- The full length isoform (isoform Long) is a daughter cell-specific cell wall protein required for efficient export of lipids such as acetylated sterols. Acts in detoxification of hydrophobic compounds. Involved in tolerance to organic solvents such as dimethyl sulfoxide (DMSO). Plays also a role as an inhibitor of mating. STE12 is utilized [...] (881 aa)    
Predicted Functional Partners:
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner; Seems to be involved in the correct timing of cell separation after cytokinesis, as separation of mutant daughter cells is delayed. Could either be an enzyme necessary for glucans- degradation of the cell wall at the neck region between mother and daughter cells or a regulatory protein controlling this metabolic step (1041 aa)
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family; Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions and plays a role in septation (420 aa)
Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP; Involved in pseudohyphal growth, cell wall metabolism and required for the separation of the mother and daughter cells (325 aa)
Hydrophilin essential in desiccation-rehydration process; cell wall protein; contains a putative GPI-attachment site; Hydrophilin which is essential to overcome the simple stress of the desiccation-rehydration process (204 aa)
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p; Involved in cell separation (542 aa)
Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of FBPase; contains CTLH domain; plays role in anti-apoptosis; Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase and required for survival upon exposure to K1 killer toxin (516 aa)
Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm; Has a role in the negative regulation of gluconeogenesis. Required for both proteasome-dependent and vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase) (921 aa)
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene (161 aa)
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR178W is not an essential gene (274 aa)
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology (273 aa)
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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