STRINGSTRING
HIT1 protein (Saccharomyces cerevisiae) - STRING interaction network
"HIT1" - Protein of unknown function, required for growth at high temperature in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
HIT1Protein of unknown function, required for growth at high temperature (164 aa)    
Predicted Functional Partners:
RSA1
Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly; Involved in a late nucleoplasmic step of 60S ribosomal subunit assembly (381 aa)
     
 
  0.938
HNT1
Adenosine 5’-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint; Hydrolyzes adenosine 5’-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha- acetyl lysine methyl ester and AMP-NH2. Essential for growth on galactose media at elevated temperatures (158 aa)
       
      0.695
AIM3
Protein interacting with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss (947 aa)
       
      0.673
PIH1
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly large protein complexes such as box C/D snoRNPs and RNA polymerase II; Involved in pre-rRNA processing and required for the NOP58-snoRNA interaction (344 aa)
       
 
  0.663
COS8
Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response (381 aa)
           
  0.640
TRM9
tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNA(Arg3) and tRNA(Glu), likely as part of a complex with Trm112p; deletion confers resistance to zymocin; Required for the methylation of the wobble bases at position 34 in tRNA. Appears to have a role in stress-response (279 aa)
           
  0.575
NOP58
Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA; Required for pre-18S rRNA processing. May bind microtubules (511 aa)
       
 
  0.574
NOP1
Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2’-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (PubMed-1825809). Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with [...] (327 aa)
       
 
  0.480
NOP56
Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2’-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects; Required for 60S ribosomal subunit synthesis (504 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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