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ECM27 protein (Saccharomyces cerevisiae) - STRING interaction network
"ECM27" - Protein of unknown function in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
ECM27Protein of unknown function; may play a role in cell wall biosynthesis, mutants are hypersensitive to anti fungal, Papulacandin B; null mutants have increased plasmid loss; interacts with Pdr5p (725 aa)    
Predicted Functional Partners:
CAF4
WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission; Involved in mitochondrial fission. Has a partially redundant function to MDV1 in acting as an adapter protein, binding to FIS1 on the mitochondrial outer membrane and recruiting the dynamin-like GTPase DNM1 to form mitochondrial fission complexes. Plays a key role in determining the polarized localization of those DNM1 clusters that are not immediately involved in the mitochondrial fi [...] (643 aa)
       
      0.699
MTF1
Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; binding of Mtf1p to the core polymerase (Rpo41p)-promoter complex s /.../zes the binding and induces DNA bending; Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner (341 aa)
       
      0.688
KHA1
Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies; Potassium-proton antiport (873 aa)
   
   
  0.583
ENA5
Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of sodium or lithium ions to allow salt tolerance (1091 aa)
         
  0.541
ECM8
Non-essential protein of unknown function; May be involved in cell wall organization and biogenesis (354 aa)
           
  0.540
VNX1
Calcium/H+ antiporter localized to the endoplasmic reticulum membrane; member of the calcium exchanger (CAX) family; potential Cdc28p substrate; Has a role in promoting intracellular monovalent cation sequestration via the exchange of monovalent cations and especially Na(+) for hydrogen ions across the vacuolar membrane (908 aa)
     
   
  0.519
ENA2
P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of sodium or lithiums ions to allow salt tolerance (1091 aa)
         
  0.504
NHX1
Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion; Endosomal/prevacuolar electroneutral Na(+)/H(+) exchanger which mediates intracellular sequestration of Na(+) cations, regulates vacuolar pH and contributes to osmotolerance following sudden exposure to hyperosmotic media. Contributes also to the postdiauxic/stationary phase resistance to osmotic stress and allows for the continued growth of cells until the acquired osmoto [...] (633 aa)
     
 
  0.500
TMN2
Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments; With EMP70 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis (672 aa)
           
  0.487
ECM19
Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; May be involved in cell wall organization and biogenesis (112 aa)
           
  0.485
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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