node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APL2 | APL3 | YKL135C | YBL037W | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | 0.977 |
APL2 | APL4 | YKL135C | YPR029C | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | 0.999 |
APL2 | APS1 | YKL135C | YLR170C | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex. | 0.999 |
APL2 | CHC1 | YKL135C | YGL206C | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | Clathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; the light chain (CLC1) is thought to regulate function. | 0.999 |
APL2 | CLC1 | YKL135C | YGR167W | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | Clathrin light chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; regulates endocytic progression; thought to regulate clathrin function; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion. | 0.977 |
APL2 | ENT3 | YKL135C | YJR125C | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | Epsin-3; Protein containing an N-terminal epsin-like domain; involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p. | 0.930 |
APL2 | ENT5 | YKL135C | YDR153C | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | Epsin-5; Protein containing an N-terminal epsin-like domain; involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin. | 0.967 |
APL2 | GGA2 | YKL135C | YHR108W | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | ADP-ribosylation factor-binding protein GGA2; Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking; binds phosphatidylinositol 4-phosphate, which plays a role in TGN localization; has homology to gamma-adaptin; GGA2 has a paralog, GGA1, that arose from the whole genome duplication. | 0.760 |
APL3 | APL2 | YBL037W | YKL135C | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | 0.977 |
APL3 | APL4 | YBL037W | YPR029C | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | 0.846 |
APL3 | APS1 | YBL037W | YLR170C | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex. | 0.971 |
APL3 | CHC1 | YBL037W | YGL206C | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | Clathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; the light chain (CLC1) is thought to regulate function. | 0.987 |
APL3 | CLC1 | YBL037W | YGR167W | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | Clathrin light chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; regulates endocytic progression; thought to regulate clathrin function; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion. | 0.975 |
APL3 | ENT3 | YBL037W | YJR125C | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | Epsin-3; Protein containing an N-terminal epsin-like domain; involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p. | 0.931 |
APL3 | ENT5 | YBL037W | YDR153C | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | Epsin-5; Protein containing an N-terminal epsin-like domain; involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin. | 0.917 |
APL4 | APL2 | YPR029C | YKL135C | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | AP-1 complex subunit beta-1; Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting; protein abundance increases in response to DNA replication stress. | 0.999 |
APL4 | APL3 | YPR029C | YBL037W | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport. | 0.846 |
APL4 | APS1 | YPR029C | YLR170C | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex. | 0.999 |
APL4 | CHC1 | YPR029C | YGL206C | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | Clathrin heavy chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion; the light chain (CLC1) is thought to regulate function. | 0.996 |
APL4 | CLC1 | YPR029C | YGR167W | AP-1 complex subunit gamma-1; Gamma-adaptin; large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport. | Clathrin light chain; subunit of the major coat protein involved in intracellular protein transport and endocytosis; regulates endocytic progression; thought to regulate clathrin function; the clathrin triskelion is a trimeric molecule composed of three heavy chains that radiate from a vertex and three light chains which bind noncovalently near the vertex of the triskelion. | 0.961 |