Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YJR146WUncharacterized protein YJR146W; Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps HMS2. (117 aa)    
Predicted Functional Partners:
YHR173C
Uncharacterized protein YHR173C; Protein of unknown function; expressed at both mRNA and protein levels; SWAT-GFP and mCherry fusion proteins localize to the vacuole.
   
  
 0.754
YNL140C
Uncharacterized protein YNL140C; Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps THO2/YNL139C.
      
 0.735
YOR105W
Uncharacterized protein YOR105W; Protein of unknown function; expressed at both mRNA and protein levels.
      
 0.734
YLR358C
Uncharacterized protein YLR358C; Protein of unknown function; expressed at both mRNA and protein levels; partially overlaps ORF RSC2/YLR357W.
   
  
 0.698
YIM2
Putative uncharacterized protein YIM2; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; not conserved in closely related Saccharomyces species; 5% of ORF overlaps the verified gene IMP1.
   
  
 0.694
YIL054W
Uncharacterized membrane protein YIL054W; Protein of unknown function; expressed at both mRNA and protein levels.
   
  
 0.693
YNL184C
Uncharacterized protein YNL184C; Protein of unknown function; expressed at both mRNA and protein levels.
   
  
 0.684
YNL319W
Putative uncharacterized protein YNL319W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HXT14.
   
  
 0.678
YBL071C
Uncharacterized protein YBL071C; Putative protein of unknown function; conserved among S. cerevisiae strains; YBL071C is not an essential gene.
   
  
 0.676
YCR013C
Putative uncharacterized protein YCR013C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; transcription of both YCR013C and the overlapping essential gene PGK1 is reduced in a gcr1 null mutant.
   
  
 0.676
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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