| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BUD16 | SNO2 | YEL029C | YNL334C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | 0.943 |
| BUD16 | SNZ2 | YEL029C | YNL333W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Probable pyridoxal 5'-phosphate synthase subunit SNZ2; Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p. | 0.936 |
| BUD16 | THI11 | YEL029C | YJR156C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI11; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP. | 0.888 |
| BUD16 | THI12 | YEL029C | YNL332W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.871 |
| BUD16 | THI13 | YEL029C | YDL244W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI13; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP. | 0.856 |
| BUD16 | THI20 | YEL029C | YOL055C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20; Trifunctional enzyme of thiamine biosynthesis, degradation and salvage; has hydroxymethylpyrimidine (HMP) kinase, HMP-phosphate (HMP-P) kinase and thiaminase activities; member of a gene family with THI21 and THI22; HMP and HMP-P kinase activity redundant with Thi21p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.620 |
| BUD16 | THI21 | YEL029C | YPL258C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21; Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.668 |
| BUD16 | THI5 | YEL029C | YFL058W | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.851 |
| BUD16 | THI6 | YEL029C | YPL214C | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | Thiamine biosynthetic bifunctional enzyme; Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.484 |
| SNO2 | BUD16 | YNL334C | YEL029C | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 0.943 |
| SNO2 | SNZ2 | YNL334C | YNL333W | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Probable pyridoxal 5'-phosphate synthase subunit SNZ2; Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p. | 0.999 |
| SNO2 | THI11 | YNL334C | YJR156C | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI11; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP. | 0.879 |
| SNO2 | THI12 | YNL334C | YNL332W | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI12; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.817 |
| SNO2 | THI13 | YNL334C | YDL244W | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI13; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP. | 0.832 |
| SNO2 | THI20 | YNL334C | YOL055C | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20; Trifunctional enzyme of thiamine biosynthesis, degradation and salvage; has hydroxymethylpyrimidine (HMP) kinase, HMP-phosphate (HMP-P) kinase and thiaminase activities; member of a gene family with THI21 and THI22; HMP and HMP-P kinase activity redundant with Thi21p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.682 |
| SNO2 | THI21 | YNL334C | YPL258C | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21; Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p; In the C-terminal section; belongs to the thiaminase-2 family. | 0.637 |
| SNO2 | THI4 | YNL334C | YGR144W | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Thiazole synthase; abundant protein involved in the formation of the thiazole moiety of thiamine during thiamine biosynthesis; acts more as a co-substrate rather than an enzyme by providing the sulphur source for thiazole formation; undergoes a single turnover only; required for mitochondrial genome stability in response to DNA damaging agents; Belongs to the THI4 family. | 0.580 |
| SNO2 | THI5 | YNL334C | YFL058W | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase THI5; Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP; Belongs to the NMT1/THI5 family. | 0.894 |
| SNO2 | THI6 | YNL334C | YPL214C | Probable pyridoxal 5'-phosphate synthase subunit SNO2; Protein of unknown function; nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin; Belongs to the glutaminase PdxT/SNO family. | Thiamine biosynthetic bifunctional enzyme; Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase; required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.594 |
| SNZ2 | BUD16 | YNL333W | YEL029C | Probable pyridoxal 5'-phosphate synthase subunit SNZ2; Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p. | Putative pyridoxal kinase; a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK). | 0.936 |
