STRINGSTRING
COS5 protein (Saccharomyces cerevisiae) - STRING interaction network
"COS5" - Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins in Saccharomyces cerevisiae
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
COS5Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (383 aa)    
Predicted Functional Partners:
COS3
Protein involved in salt resistance; interacts with sodium-hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (379 aa)
     
   
0.933
COS4
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (379 aa)
     
     
0.931
COS7
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (383 aa)
     
     
0.918
COS2
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (379 aa)
     
   
0.872
COS1
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (381 aa)
     
     
0.842
COS8
Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response (381 aa)
     
   
0.839
RBA50
Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (439 aa)
           
  0.697
RSP5
E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates an /.../dy; ubiquitylates Sec23p; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Component of a RSP5 ubiquitin ligase complex which specifies polyubiquitination and intracellular trafficking of the general a [...] (809 aa)
       
      0.577
YIL102C
Putative protein of unknown function (101 aa)
           
  0.575
ABM1
Protein of unknown function, required for normal microtubule organization; Required for normal microtubule organization (123 aa)
           
  0.520
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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