node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AST1 | YDL121C | YBL069W | YDL121C | Putative uncharacterized protein ybl068w-a; Protein AST1; Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication | Uncharacterized protein YDL121C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein | 0.674 |
AST1 | YKL077W | YBL069W | YKL077W | Putative uncharacterized protein ybl068w-a; Protein AST1; Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.680 |
AST2 | YDL121C | YER101C | YDL121C | Protein AST2; Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication | Uncharacterized protein YDL121C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein | 0.775 |
AST2 | YKL077W | YER101C | YKL077W | Protein AST2; Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.779 |
EPS1 | YKL077W | YIL005W | YKL077W | ER-retained PMA1-suppressing protein 1; ER protein with chaperone and co-chaperone activity; involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.607 |
GDT1 | UIP5 | YBR187W | YKR044W | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | Protein uip5; Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates | 0.780 |
GDT1 | YIL067C | YBR187W | YIL067C | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | Uncharacterized protein yil067c; Uncharacterized protein of unknown function | 0.780 |
GDT1 | YKL077W | YBR187W | YKL077W | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.744 |
GDT1 | YNL115C | YBR187W | YNL115C | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | Uncharacterized vacuolar membrane protein YNL115C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene | 0.749 |
GDT1 | YOR292C | YBR187W | YOR292C | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | Vacuolar membrane protein YOR292C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene; Belongs to the peroxisomal membrane protein PXMP2/4 family | 0.745 |
PRM2 | YKL077W | YIL037C | YKL077W | Pheromone-regulated protein; predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.699 |
UIP5 | GDT1 | YKR044W | YBR187W | Protein uip5; Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | 0.780 |
UIP5 | YIL067C | YKR044W | YIL067C | Protein uip5; Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates | Uncharacterized protein yil067c; Uncharacterized protein of unknown function | 0.912 |
UIP5 | YKL077W | YKR044W | YKL077W | Protein uip5; Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.864 |
UIP5 | YNL115C | YKR044W | YNL115C | Protein uip5; Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates | Uncharacterized vacuolar membrane protein YNL115C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene | 0.863 |
UIP5 | YOR292C | YKR044W | YOR292C | Protein uip5; Protein of unknown function that interacts with Ulp1p; a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates | Vacuolar membrane protein YOR292C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene; Belongs to the peroxisomal membrane protein PXMP2/4 family | 0.866 |
YDL121C | AST1 | YDL121C | YBL069W | Uncharacterized protein YDL121C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein | Putative uncharacterized protein ybl068w-a; Protein AST1; Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication | 0.674 |
YDL121C | AST2 | YDL121C | YER101C | Uncharacterized protein YDL121C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein | Protein AST2; Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication | 0.775 |
YDL121C | YKL077W | YDL121C | YKL077W | Uncharacterized protein YDL121C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDL121C is not an essential protein | Uncharacterized protein YKL077W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole | 0.870 |
YIL067C | GDT1 | YIL067C | YBR187W | Uncharacterized protein yil067c; Uncharacterized protein of unknown function | GCR1-dependent translation factor 1; Calcium transporter localized to the cis- and medial-Golgi apparatus; required for protein glycosylation; GFP-fusion protein localizes to the vacuole; TMEM165, a human gene which causes Congenital Disorders of Glycosylation is orthologous and functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression reduced in a gcr1 null mutant; Belongs to the GDT1 family | 0.780 |