node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBC2 | GIS2 | YPL178W | YNL255C | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2. | 0.582 |
CBC2 | NAB2 | YPL178W | YGL122C | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family. | 0.996 |
CBC2 | YDR521W | YPL178W | YDR521W | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | 0.559 |
CBC2 | YKL102C | YPL178W | YKL102C | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | Uncharacterized protein YKL102C; Putative protein of unknown function; conserved across S. cerevisiae strains; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site. | 0.559 |
CBC2 | YLL066W-A | YPL178W | YLL066W-A | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YLL066C. | 0.559 |
GAT3 | YDR521W | YLR013W | YDR521W | Protein containing GATA family zinc finger motifs; involved in spore wall assembly; sequence similarity to GAT4, and the double mutant gat3 gat4 exhibits reduced dityrosine fluorescence relative to the single mutants. | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | 0.759 |
GAT3 | YKL102C | YLR013W | YKL102C | Protein containing GATA family zinc finger motifs; involved in spore wall assembly; sequence similarity to GAT4, and the double mutant gat3 gat4 exhibits reduced dityrosine fluorescence relative to the single mutants. | Uncharacterized protein YKL102C; Putative protein of unknown function; conserved across S. cerevisiae strains; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site. | 0.762 |
GAT3 | YLL066W-A | YLR013W | YLL066W-A | Protein containing GATA family zinc finger motifs; involved in spore wall assembly; sequence similarity to GAT4, and the double mutant gat3 gat4 exhibits reduced dityrosine fluorescence relative to the single mutants. | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YLL066C. | 0.763 |
GIS2 | CBC2 | YNL255C | YPL178W | Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2. | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | 0.582 |
GIS2 | YDR521W | YNL255C | YDR521W | Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2. | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | 0.632 |
GIS2 | YKL102C | YNL255C | YKL102C | Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2. | Uncharacterized protein YKL102C; Putative protein of unknown function; conserved across S. cerevisiae strains; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site. | 0.632 |
GIS2 | YLL066W-A | YNL255C | YLL066W-A | Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2. | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YLL066C. | 0.632 |
NAB2 | CBC2 | YGL122C | YPL178W | Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family. | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | 0.996 |
NAB2 | YDR521W | YGL122C | YDR521W | Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family. | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | 0.551 |
NAB2 | YKL102C | YGL122C | YKL102C | Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family. | Uncharacterized protein YKL102C; Putative protein of unknown function; conserved across S. cerevisiae strains; deletion confers sensitivity to citric acid; predicted protein would include a thiol-disulfide oxidoreductase active site. | 0.551 |
NAB2 | YLL066W-A | YGL122C | YLL066W-A | Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family. | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the uncharacterized ORF YLL066C. | 0.551 |
YDR521W | CBC2 | YDR521W | YPL178W | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | Nuclear cap-binding protein subunit 2; Small subunit of the heterodimeric cap binding complex with Sto1p; interacts with Npl3p, possibly to package mRNA for export from the nucleus; may have a role in telomere maintenance; contains an RNA-binding motif; Belongs to the RRM NCBP2 family. | 0.559 |
YDR521W | GAT3 | YDR521W | YLR013W | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | Protein containing GATA family zinc finger motifs; involved in spore wall assembly; sequence similarity to GAT4, and the double mutant gat3 gat4 exhibits reduced dityrosine fluorescence relative to the single mutants. | 0.759 |
YDR521W | GIS2 | YDR521W | YNL255C | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | Zinc finger protein GIS2; Translational activator for mRNAs with internal ribosome entry sites; associates with polysomes and binds to a specific subset of mRNAs; localizes to RNA processing bodies (P bodies) and to stress granules; may have a role in translation regulation under stress conditions; ortholog of human ZNF9/CNBP, a gene involved in myotonic dystrophy type 2. | 0.632 |
YDR521W | NAB2 | YDR521W | YGL122C | Putative uncharacterized protein YDR521W; Dubious ORF that overlaps YDR520C; mutant increases expression of PIS1 and RPL3 in glycerol. | Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs; Belongs to the NAB2 family. | 0.551 |