node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IMG1 | IMG2 | YCR046C | YCR071C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | 0.999 |
IMG1 | MRPL13 | YCR046C | YKR006C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; not essential for mitochondrial translation. | 0.977 |
IMG1 | MRPL15 | YCR046C | YLR312W-A | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily. | 0.971 |
IMG1 | MRPL16 | YCR046C | YBL038W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation. | 0.999 |
IMG1 | MRPL3 | YCR046C | YMR024W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily. | 0.999 |
IMG1 | MRPL35 | YCR046C | YDR322W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily. | 0.995 |
IMG1 | MRPL36 | YCR046C | YBR122C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region. | 0.982 |
IMG1 | MRPL51 | YCR046C | YPR100W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.998 |
IMG1 | MRPL9 | YCR046C | YGR220C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG1 | YML6 | YCR046C | YML025C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins. | 0.999 |
IMG2 | IMG1 | YCR071C | YCR046C | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | 0.999 |
IMG2 | MRPL13 | YCR071C | YKR006C | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; not essential for mitochondrial translation. | 0.953 |
IMG2 | MRPL15 | YCR071C | YLR312W-A | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily. | 0.949 |
IMG2 | MRPL16 | YCR071C | YBL038W | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation. | 0.997 |
IMG2 | MRPL3 | YCR071C | YMR024W | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; located in close proximity to the polypeptide exit channel of the ribosome; mutations in human homolog MRPL44 cause childhood cardiomyopathy; human MRPL44 deficiency results in inefficient assembly of the mitochondrial ribosome, and in tissue-specific respiratory chain deficiency, manifesting as either Complex I+Complex IV or Complex IV deficiency, depending on a cell type; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily. | 0.999 |
IMG2 | MRPL35 | YCR071C | YDR322W | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily. | 0.991 |
IMG2 | MRPL36 | YCR071C | YBR122C | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region. | 0.957 |
IMG2 | MRPL51 | YCR071C | YPR100W | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG2 | MRPL9 | YCR071C | YGR220C | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit. | 0.998 |
IMG2 | YML6 | YCR071C | YML025C | Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49. | Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins. | 0.998 |