node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADP1 | BPT1 | YCR011C | YLL015W | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | 0.574 |
ADP1 | NFT1 | YCR011C | YKR103W | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | ABC transporter NFT1; Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein. | 0.616 |
ADP1 | VMR1 | YCR011C | YHL035C | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | ABC transporter ATP-binding protein/permease VMR1; Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication. | 0.415 |
ADP1 | YBT1 | YCR011C | YLL048C | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | ATP-dependent bile acid permease; Transporter of the ATP-binding cassette (ABC) family; involved in bile acid transport; negative regulator of vacuole fusion; regulates release of lumenal Ca2+ stores; similar to mammalian bile transporters; YBT1 has a paralog, VMR1, that arose from the whole genome duplication. | 0.417 |
ADP1 | YCF1 | YCR011C | YDR135C | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | Metal resistance protein YCF1; Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. | 0.514 |
ADP1 | YOR1 | YCR011C | YGR281W | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | Oligomycin resistance ATP-dependent permease YOR1; Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter mediates export of many different organic anions including oligomycin; homolog of human cystic fibrosis transmembrane receptor (CFTR). | 0.563 |
BPT1 | ADP1 | YLL015W | YCR011C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | 0.574 |
BPT1 | NFT1 | YLL015W | YKR103W | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | ABC transporter NFT1; Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein. | 0.632 |
BPT1 | PDR11 | YLL015W | YIL013C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | ATP-dependent permease PDR11; ATP-binding cassette (ABC) transporter; multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromised; regulated by Pdr1p; required for anaerobic growth; PDR11 has a paralog, AUS1, that arose from the whole genome duplication; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. | 0.537 |
BPT1 | PDR12 | YLL015W | YPL058C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | ATP-dependent permease PDR12; Plasma membrane ATP-binding cassette (ABC) transporter; weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity. | 0.589 |
BPT1 | PDR15 | YLL015W | YDR406W | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | ATP-dependent permease PDR15; Plasma membrane ATP binding cassette (ABC) transporter; multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element; PDR15 has a paralog, PDR5, that arose from the whole genome duplication. | 0.594 |
BPT1 | VMR1 | YLL015W | YHL035C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | ABC transporter ATP-binding protein/permease VMR1; Vacuolar membrane protein; involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions; VMR1 has a paralog, YBT1, that arose from the whole genome duplication. | 0.599 |
BPT1 | YBT1 | YLL015W | YLL048C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | ATP-dependent bile acid permease; Transporter of the ATP-binding cassette (ABC) family; involved in bile acid transport; negative regulator of vacuole fusion; regulates release of lumenal Ca2+ stores; similar to mammalian bile transporters; YBT1 has a paralog, VMR1, that arose from the whole genome duplication. | 0.612 |
BPT1 | YCF1 | YLL015W | YDR135C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | Metal resistance protein YCF1; Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR; Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. | 0.966 |
BPT1 | YOL075C | YLL015W | YOL075C | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | Uncharacterized ABC transporter ATP-binding protein/permease YOL075C; Putative ABC transporter; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. | 0.592 |
BPT1 | YOR1 | YLL015W | YGR281W | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | Oligomycin resistance ATP-dependent permease YOR1; Plasma membrane ATP-binding cassette (ABC) transporter; multidrug transporter mediates export of many different organic anions including oligomycin; homolog of human cystic fibrosis transmembrane receptor (CFTR). | 0.930 |
NFT1 | ADP1 | YKR103W | YCR011C | ABC transporter NFT1; Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein. | Putative ATP-dependent permease of the ABC transporter family; Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. | 0.616 |
NFT1 | BPT1 | YKR103W | YLL015W | ABC transporter NFT1; Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein. | Bile pigment transporter 1; ABC type transmembrane transporter of MRP/CFTR family; found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p. | 0.632 |
NFT1 | PDR11 | YKR103W | YIL013C | ABC transporter NFT1; Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein. | ATP-dependent permease PDR11; ATP-binding cassette (ABC) transporter; multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromised; regulated by Pdr1p; required for anaerobic growth; PDR11 has a paralog, AUS1, that arose from the whole genome duplication; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. | 0.721 |
NFT1 | PDR12 | YKR103W | YPL058C | ABC transporter NFT1; Putative transporter of the MRP subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds; MRP stands for multidrug resistance-associated protein. | ATP-dependent permease PDR12; Plasma membrane ATP-binding cassette (ABC) transporter; weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity. | 0.562 |