node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAD14 | YLL053C | YNL331C | YLL053C | Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin. | 0.574 |
AAD14 | YLL054C | YNL331C | YLL054C | Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.483 |
IES1 | IES4 | YFL013C | YOR189W | Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia. | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | 0.999 |
IES1 | TBS1 | YFL013C | YBR150C | Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia. | Uncharacterized transcriptional regulatory protein TBS1; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication. | 0.476 |
IES1 | YLL054C | YFL013C | YLL054C | Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.507 |
IES1 | YLR278C | YFL013C | YLR278C | Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia. | Uncharacterized transcriptional regulatory protein YLR278C; Zinc-cluster protein; GFP-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; has a prion-domain like fragment that increases frequency of [URE3]; YLR278C is not an essential gene. | 0.498 |
IES4 | IES1 | YOR189W | YFL013C | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia. | 0.999 |
IES4 | TBS1 | YOR189W | YBR150C | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | Uncharacterized transcriptional regulatory protein TBS1; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication. | 0.414 |
IES4 | YLL054C | YOR189W | YLL054C | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.471 |
IES4 | YLR278C | YOR189W | YLR278C | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | Uncharacterized transcriptional regulatory protein YLR278C; Zinc-cluster protein; GFP-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; has a prion-domain like fragment that increases frequency of [URE3]; YLR278C is not an essential gene. | 0.444 |
LDB18 | YLL053C | YLL049W | YLL053C | Protein LDB18; Component of the dynactin complex; dynactin is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24. | Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin. | 0.492 |
LDB18 | YLL054C | YLL049W | YLL054C | Protein LDB18; Component of the dynactin complex; dynactin is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.561 |
PBN1 | YLL054C | YCL052C | YLL054C | Protein PBN1; Component of glycosylphosphatidylinositol-mannosyltransferase I; essential component; required for the autocatalytic post-translational processing of the protease B precursor Prb1p; localizes to ER in lumenal orientation; homolog of mammalian PIG-X. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.654 |
TBS1 | IES1 | YBR150C | YFL013C | Uncharacterized transcriptional regulatory protein TBS1; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication. | Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia. | 0.476 |
TBS1 | IES4 | YBR150C | YOR189W | Uncharacterized transcriptional regulatory protein TBS1; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication. | Ino eighty subunit 4; Component of the INO80 chromatiin remodeling complex; target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses. | 0.414 |
TBS1 | YLL054C | YBR150C | YLL054C | Uncharacterized transcriptional regulatory protein TBS1; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.698 |
TBS1 | YLR278C | YBR150C | YLR278C | Uncharacterized transcriptional regulatory protein TBS1; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; TBS1 has a paralog, HAL9, that arose from the whole genome duplication. | Uncharacterized transcriptional regulatory protein YLR278C; Zinc-cluster protein; GFP-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; has a prion-domain like fragment that increases frequency of [URE3]; YLR278C is not an essential gene. | 0.616 |
YCT1 | YLL054C | YLL055W | YLL054C | High-affinity cysteine-specific transporter; has similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene; Belongs to the major facilitator superfamily. Allantoate permease family. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.841 |
YLL037W | YLL054C | YLL037W | YLL054C | Putative uncharacterized protein YLL037W; Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential PRP19 gene encoding an RNA splicing factor. | Uncharacterized transcriptional regulatory protein YLL054C; Putative protein of unknown function with similarity to Pip2p; an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene. | 0.610 |
YLL053C | AAD14 | YLL053C | YNL331C | Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin. | Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | 0.574 |