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AYT1 protein (Saccharomyces cerevisiae) - STRING interaction network
"AYT1" - Acetyltransferase in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AYT1Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis; Trichothecene 3-O-acetyltransferase involved in self- protection against trichothecenes, mycotoxins acting as eukaryotic protein synthesis inhibitors. Its existence is surprising in a non-trichothecene producer organism which needs no self-protection again endogenic trichothecenes. The persistence of this non- essential gene may be due to a selective advantage that it may confer, like a resistance to exogenic trichothecenes (474 aa)    
Predicted Functional Partners:
TRI1
Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus; May be involved in transcription regulation (226 aa)
           
  0.892
PAF1
Component of the Paf1p complex involved in transcription elongation; binds to and modulates the activity of RNA polymerases I and II; required for expression of a subset of genes, including cell cycle-regulated genes; involved in SER3 repression by /.../g to maintain SRG1 transcription-dependent nucleosome occupancy; homolog of human PD2/hPAF1; The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA- binding proteins. Involved in elongation. It regulates 3’-end formation of snR47 by modulating the recruitment or stable ass [...] (445 aa)
       
 
  0.679
ARA2
NAD-dependent arabinose dehydrogenase, involved in biosynthesis of dehydro-D-arabinono-1,4-lactone; similar to plant L-galactose dehydrogenase (335 aa)
       
      0.677
YOL160W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data (113 aa)
           
  0.571
MGL2
Putative acyltransferase with similarity to Eeb1p and Eht1p, has a minor role in medium-chain fatty acid ethyl ester biosynthesis; may be involved in lipid metabolism and detoxification (449 aa)
           
  0.487
YPL257W
Putative protein of unknown function; homozygous diploid deletion strain exhibits low budding index; physically interacts with Hsp82p; YPL257W is not an essential gene; May be required for cell cycle progression (193 aa)
           
  0.445
YHR214W-A
Dubious open reading frame; induced by zinc deficiency; YHR214W-A has a paralog, YAR068W, that arose from a segmental duplication (161 aa)
           
  0.444
EEB1
Acyl-coenzymeA-ethanol O-acyltransferase responsible for the major part of medium-chain fatty acid ethyl ester biosynthesis during fermentation; possesses short-chain esterase activity; may be involved in lipid metabolism and detoxification; Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by esterification (456 aa)
           
  0.442
PDR5
Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth; Active efflux of weakly charged organic compounds of 90 cubic Angstroms to 300 cubic Angstroms surface volume. Confers resistance to numerous chemicals including cycloheximide, sulfomethuron methyl, steroids, antiseptics, antibiotics, anticancer, herbicides, mycotoxins, insecticides, ionophores, alkaloids, flavonoids, phenothiazines, organotin compounds, carbazoles, lysoso [...] (1511 aa)
           
  0.418
MTC3
Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; mtc3 is synthetically sick with cdc13-1; May be involved in telomere capping (123 aa)
           
  0.418
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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