Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
YLL065WPutative UPF0320 protein YLL065W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps chromosome XII telomeric element core sequences. (116 aa)    
Predicted Functional Partners:
YKR040C
Putative uncharacterized protein YKR040C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YKR041W.
   
  
 0.837
YLL066W-B
Uncharacterized protein YLL066W-B; Putative protein of unknown function; overexpression causes a cell cycle delay or arrest.
   
  
 0.765
YHR217C
Putative uncharacterized protein YHR217C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R.
   
  
 0.680
YML122C
Uncharacterized protein YML122C; Putative protein of unknown function; conserved among S. cerevisiae strains; YML122C is not an essential gene.
   
  
 0.667
SOH1
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits.
   
   0.611
YNR077C
UPF0320 protein YNR077C; Protein of unknown function, abundance changes with carbon source.
   
   
0.601
YJR162C
Putative UPF0320 protein YJR162C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
   
0.485
ECM34
Protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; SWAT-GFP, seamless-GFP and mCherry C-terminal fusion proteins localize to the cytosol; Belongs to the DUP/COS family.
      
 0.458
CEM1
3-oxoacyl-[acyl-carrier-protein] synthase homolog; Mitochondrial beta-keto-acyl synthase; possible role in fatty acid synthesis; required for mitochondrial respiration; human homolog OXSM can complement yeast cem1 null mutant; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
      
 0.415
TDA1
Serine/threonine-protein kinase TDA1; Protein kinase of unknown cellular role; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene; relocalizes from nucleus to cytoplasm upon DNA replication stress.
      
 0.415
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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