node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE2 | YLR001C | YLR131C | YLR001C | Metallothionein expression activator; Transcription factor required for septum destruction after cytokinesis; phosphorylation by Cbk1p blocks nuclear exit during M/G1 transition, causing localization to daughter cell nuclei, and also increases Ace2p activity; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of RAM network that regulates cellular polarity and morphogenesis; ACE2 has a paralog, SWI5, that arose from the whole genome duplication | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.599 |
DNM1 | YLR001C | YLL001W | YLR001C | Dynamin-related protein DNM1; Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.696 |
ENB1 | YLR001C | YOL158C | YLR001C | Mfs transporter, sit family, siderophore-iron:h+ symporter; Siderophore iron transporter ENB1; Endosomal ferric enterobactin transporter; expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.748 |
ENB1 | YLR125W | YOL158C | YLR125W | Mfs transporter, sit family, siderophore-iron:h+ symporter; Siderophore iron transporter ENB1; Endosomal ferric enterobactin transporter; expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment | Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene | 0.522 |
GLN4 | PNS1 | YOR168W | YOR161C | Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family | Protein pns1; Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport | 0.590 |
GLN4 | TFC3 | YOR168W | YAL001C | Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family | Subunit of RNA polymerase III transcription initiation factor complex; part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding; largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC) | 0.647 |
GLN4 | YLR001C | YOR168W | YLR001C | Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.647 |
HSV2 | PNS1 | YGR223C | YOR161C | SVP1-like protein 2; Phosphatidylinositol 3,5-bisphosphate-binding protein; plays a role in micronucleophagy; belongs to the PROPPIN family of proteins; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization; Belongs to the WD repeat SVP1 family | Protein pns1; Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport | 0.563 |
HSV2 | YLR001C | YGR223C | YLR001C | SVP1-like protein 2; Phosphatidylinositol 3,5-bisphosphate-binding protein; plays a role in micronucleophagy; belongs to the PROPPIN family of proteins; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization; Belongs to the WD repeat SVP1 family | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.644 |
PNS1 | GLN4 | YOR161C | YOR168W | Protein pns1; Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport | Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family | 0.590 |
PNS1 | HSV2 | YOR161C | YGR223C | Protein pns1; Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport | SVP1-like protein 2; Phosphatidylinositol 3,5-bisphosphate-binding protein; plays a role in micronucleophagy; belongs to the PROPPIN family of proteins; predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization; Belongs to the WD repeat SVP1 family | 0.563 |
PNS1 | YLR001C | YOR161C | YLR001C | Protein pns1; Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.618 |
SHE4 | YLR001C | YOR035C | YLR001C | SWI5-dependent HO expression protein 4; Protein containing a UCS (UNC-45/CRO1/SHE4) domain; binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.639 |
SSF2 | YLR001C | YDR312W | YLR001C | Ribosome biogenesis protein SSF2; Protein required for ribosomal large subunit maturation; functionally redundant with Ssf1p; member of the Brix family; SSF2 has a paralog, SSF1, that arose from the whole genome duplication | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.697 |
TFC3 | GLN4 | YAL001C | YOR168W | Subunit of RNA polymerase III transcription initiation factor complex; part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding; largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC) | Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family | 0.647 |
TFC3 | YLR001C | YAL001C | YLR001C | Subunit of RNA polymerase III transcription initiation factor complex; part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding; largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC) | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | 0.784 |
YLR001C | ACE2 | YLR001C | YLR131C | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | Metallothionein expression activator; Transcription factor required for septum destruction after cytokinesis; phosphorylation by Cbk1p blocks nuclear exit during M/G1 transition, causing localization to daughter cell nuclei, and also increases Ace2p activity; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of RAM network that regulates cellular polarity and morphogenesis; ACE2 has a paralog, SWI5, that arose from the whole genome duplication | 0.599 |
YLR001C | DNM1 | YLR001C | YLL001W | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | Dynamin-related protein DNM1; Dynamin-related GTPase involved in mitochondrial organization; required for mitochondrial fission and inheritance; self assembles on the cytoplasmic face of mitochondrial tubules at sites where division will occur; participates in endocytosis and regulates peroxisome fission along with Vps1p; mutants in the human ortholog DNM1L, which mediates mitochondrial fission, peroxisomal division, autophagy, and mitophagy, are associated with slowly progressive infantile encephalopathy | 0.696 |
YLR001C | ENB1 | YLR001C | YOL158C | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | Mfs transporter, sit family, siderophore-iron:h+ symporter; Siderophore iron transporter ENB1; Endosomal ferric enterobactin transporter; expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment | 0.748 |
YLR001C | GLN4 | YLR001C | YOR168W | FAS1 domain-containing protein YLR001C; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated | Glutamine--tRNA ligase; Glutamine tRNA synthetase; monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Gln); N-terminal domain proposed to be involved in enzyme-tRNA interactions; Belongs to the class-I aminoacyl-tRNA synthetase family | 0.647 |