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GEP5 protein (Saccharomyces cerevisiae) - STRING interaction network
"GEP5" - Protein of unknown function, required for mitochondrial genome maintenance in Saccharomyces cerevisiae
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GEP5Protein of unknown function, required for mitochondrial genome maintenance; detected in highly purified mitochondria in high-throughput studies; null mutant has decreased levels of cardiolipin and phosphatidylethanolamine; Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins (293 aa)    
Predicted Functional Partners:
RRG8
Protein of unknown function; required for mitochondrial genome maintenance; null mutation results in a decrease in plasma membrane electron transport; Required for respiratory activity and maintenance and expression of the mitochondrial genome (277 aa)
       
 
  0.876
YAL065C
Putative protein of unknown function; has homology to FLO1; possible pseudogene (128 aa)
           
  0.744
RRG9
Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Required for respiratory activity and maintenance and expression of the mitochondrial genome (214 aa)
           
  0.697
GDS1
Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Involved in nuclear control of mitochondria (522 aa)
       
      0.680
SRL4
Protein of unknown function; involved in regulation of dNTP production; null mutant suppresses the lethality of lcd1 and rad53 mutations; expression is induced by Kar4p; May be involved in the regulation of dNTP production. Induces the SOS system when expressed in E.coli, therefore, it may play a role in DNA metabolism and/or in genome stability (281 aa)
           
  0.625
YER158C
Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p (573 aa)
           
  0.578
HER2
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). Required for HMG2-induced ER-remodeling (464 aa)
           
  0.574
COX16
Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase; Required for the assembly of cytochrome c oxidase (118 aa)
           
  0.574
YMR31
Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36 (123 aa)
           
  0.572
APA1
Diadenosine 5’,5’’-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5’-nucleosidyl) tetraphosphates; has similarity to Apa2p; Ap4A phosphorylase catalyzes the phosphorolytic degradation of bis(5’-adenosyl) tetraphosphate (Ap4A) into ADP and ATP. Can also use other Np4N’ nucleotides (where N and N’ stand for A,C,G or U) as substrates with equal efficiency. Cannot catalyze the reverse reaction. Additionally, this enzyme can also catalyze the phosphorolytic degradation of adenosine 5’- phosphosulfate (AMPS) into ADP and sulfate, the reversible excha [...] (321 aa)
           
  0.572
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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