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YLR108C protein (Saccharomyces cerevisiae) - STRING interaction network
"YLR108C" - Protein of unknown function in Saccharomyces cerevisiae
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
YLR108CProtein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene (485 aa)    
Predicted Functional Partners:
YNR014W
Putative protein of unknown function; expression is cell-cycle regulated, Azf1p-dependent, and heat-inducible (212 aa)
           
  0.697
GRE2
3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway; Catalyzes the irreversible reduction of the cytotoxic compound methylglyoxal (MG) to (S)-lactaldehyde as an alternative to detoxification of MG by glyoxalase I GLO1. MG is synthesized via a bypath of glycolysis from dihydroxyacetone phosphate and is believed to play a role in cell cycle regulation and stress adaptation. Also catalyzes the reduction of 3-methylbutanal to 3- methylbutan [...] (342 aa)
     
        0.593
MPO1
Putative protein of unknown function; YGL010W is not an essential gene; Not an essential protein for cell growth (174 aa)
     
   
  0.540
YDL109C
Putative lipase; involved in lipid metabolism; YDL109C is not an essential gene; Involved in lipid metabolism (647 aa)
           
  0.515
SPG3
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; Required for survival during stationary phase (127 aa)
           
  0.489
AIM23
Mitochondrial translation initiation factor 3 (IF3, mIF3); evolutionarily conserved; binds to E. coli ribosomes in vitro; null mutant displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss (356 aa)
           
  0.487
YGL242C
Putative protein of unknown function; deletion mutant is viable (181 aa)
           
  0.487
YCR101C
Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene (182 aa)
           
  0.485
POF1
Protein involved in the filamentation pathway; interacts physically with Kss1p and suppresses the filamentation defect of a kss1 deletion; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Involved in the salvage pathway for NAD(+) biosynthesis via NMN (PubMed-24759102). Involved in the filamentation pathway. Suppresses the filamentation defect of a KSS1 deletion (PubMed-21460040) (258 aa)
           
  0.481
YKR011C
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus (353 aa)
     
   
  0.477
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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