| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCW12 | YLR111W | YLR110C | YLR111W | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.664 |
| EOS1 | YLR111W | YNL080C | YLR111W | Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene; Belongs to the EOS1 family. | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.671 |
| NUM1 | TPM1 | YDR150W | YNL079C | Protein required for nuclear migration; component of the mitochondria-ER-cortex-ancor (MECA); required for the association of mitochondria with the cell cortex and for accurate distribution of mitochondrial network; interacts with Mdm36p to link the ER and mitochondria at the cortex; localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex. | Tropomyosin-1; Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication. | 0.458 |
| NUM1 | YLR111W | YDR150W | YLR111W | Protein required for nuclear migration; component of the mitochondria-ER-cortex-ancor (MECA); required for the association of mitochondria with the cell cortex and for accurate distribution of mitochondrial network; interacts with Mdm36p to link the ER and mitochondria at the cortex; localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex. | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.430 |
| SPT8 | YLR111W | YLR055C | YLR111W | Transcription factor SPT8; Subunit of the SAGA transcriptional regulatory complex; not present in SAGA-like complex SLIK/SALSA; required for SAGA-mediated inhibition at some promoters. | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.415 |
| TPM1 | NUM1 | YNL079C | YDR150W | Tropomyosin-1; Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication. | Protein required for nuclear migration; component of the mitochondria-ER-cortex-ancor (MECA); required for the association of mitochondria with the cell cortex and for accurate distribution of mitochondrial network; interacts with Mdm36p to link the ER and mitochondria at the cortex; localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex. | 0.458 |
| TPM1 | YLR111W | YNL079C | YLR111W | Tropomyosin-1; Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication. | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.430 |
| YLR111W | CCW12 | YLR111W | YLR110C | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | 0.664 |
| YLR111W | EOS1 | YLR111W | YNL080C | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene; Belongs to the EOS1 family. | 0.671 |
| YLR111W | NUM1 | YLR111W | YDR150W | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Protein required for nuclear migration; component of the mitochondria-ER-cortex-ancor (MECA); required for the association of mitochondria with the cell cortex and for accurate distribution of mitochondrial network; interacts with Mdm36p to link the ER and mitochondria at the cortex; localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex. | 0.430 |
| YLR111W | SPT8 | YLR111W | YLR055C | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Transcription factor SPT8; Subunit of the SAGA transcriptional regulatory complex; not present in SAGA-like complex SLIK/SALSA; required for SAGA-mediated inhibition at some promoters. | 0.415 |
| YLR111W | TPM1 | YLR111W | YNL079C | Uncharacterized protein YLR111W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Tropomyosin-1; Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently; TPM1 has a paralog, TPM2, that arose from the whole genome duplication. | 0.430 |
