node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSM4 | YLR173W | YPL200W | YLR173W | Protein required for accurate chromosome segregation during meiosis; involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements; functions with meiosis-specific telomere-binding protein Ndj1p; CSM4 has a paralog, MPS2, that arose from the whole genome duplication. | Putative protein of unknown function. | 0.459 |
LAM6 | YLR173W | YLR072W | YLR173W | Membrane-anchored lipid-binding protein LAM6; Sterol transporter that transfers sterols between membranes; may regulate and coordinate formation of contact sites between organelles; localizes to ER-mitochondrial contact sites in a Tom70p- and Tom71p-dependent manner; mitochondrial localization requires GRAM domain; also localizes to ER-vacuole contact sites, in a Vac8p-dependent manner; has GRAM and StART-like (VASt) domains; one of six StART-like domain-containing proteins in yeast; conserved across eukaryotes; Belongs to the YSP2 family. | Putative protein of unknown function. | 0.444 |
MCH2 | YLR173W | YKL221W | YLR173W | Probable transporter MCH2; Protein with similarity to mammalian monocarboxylate permeases; monocarboxylate permeases are involved in transport of monocarboxylic acids across the plasma membrane but mutant is not deficient in monocarboxylate transport; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | Putative protein of unknown function. | 0.489 |
PCD1 | YLR173W | YLR151C | YLR173W | Peroxisomal coenzyme A diphosphatase 1, peroxisomal; 8-oxo-dGTP diphosphatase; prevents spontaneous mutagenesis via sanitization of oxidized purine nucleoside triphosphates; can also act as peroxisomal pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids; nudix hydrolase family member; similar E. coli MutT and human, rat and mouse MTH1. | Putative protein of unknown function. | 0.490 |
RMD6 | YLR173W | YEL072W | YLR173W | Protein required for sporulation. | Putative protein of unknown function. | 0.446 |
SNL1 | YLR173W | YIL016W | YLR173W | HSP70 co-chaperone SNL1; Ribosome-associated protein; proposed to act in protein synthesis and nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein. | Putative protein of unknown function. | 0.420 |
YBR116C | YLR173W | YBR116C | YLR173W | Putative uncharacterized protein YBR116C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TKL2. | Putative protein of unknown function. | 0.453 |
YKL071W | YLR173W | YKL071W | YLR173W | Uncharacterized oxidoreductase YKL071W; Putative protein of unknown function; expression induced in cells treated with the mycotoxin patulin, and also the quinone methide triterpene celastrol; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Putative protein of unknown function. | 0.543 |
YLR173W | CSM4 | YLR173W | YPL200W | Putative protein of unknown function. | Protein required for accurate chromosome segregation during meiosis; involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements; functions with meiosis-specific telomere-binding protein Ndj1p; CSM4 has a paralog, MPS2, that arose from the whole genome duplication. | 0.459 |
YLR173W | LAM6 | YLR173W | YLR072W | Putative protein of unknown function. | Membrane-anchored lipid-binding protein LAM6; Sterol transporter that transfers sterols between membranes; may regulate and coordinate formation of contact sites between organelles; localizes to ER-mitochondrial contact sites in a Tom70p- and Tom71p-dependent manner; mitochondrial localization requires GRAM domain; also localizes to ER-vacuole contact sites, in a Vac8p-dependent manner; has GRAM and StART-like (VASt) domains; one of six StART-like domain-containing proteins in yeast; conserved across eukaryotes; Belongs to the YSP2 family. | 0.444 |
YLR173W | MCH2 | YLR173W | YKL221W | Putative protein of unknown function. | Probable transporter MCH2; Protein with similarity to mammalian monocarboxylate permeases; monocarboxylate permeases are involved in transport of monocarboxylic acids across the plasma membrane but mutant is not deficient in monocarboxylate transport; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | 0.489 |
YLR173W | PCD1 | YLR173W | YLR151C | Putative protein of unknown function. | Peroxisomal coenzyme A diphosphatase 1, peroxisomal; 8-oxo-dGTP diphosphatase; prevents spontaneous mutagenesis via sanitization of oxidized purine nucleoside triphosphates; can also act as peroxisomal pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids; nudix hydrolase family member; similar E. coli MutT and human, rat and mouse MTH1. | 0.490 |
YLR173W | RMD6 | YLR173W | YEL072W | Putative protein of unknown function. | Protein required for sporulation. | 0.446 |
YLR173W | SNL1 | YLR173W | YIL016W | Putative protein of unknown function. | HSP70 co-chaperone SNL1; Ribosome-associated protein; proposed to act in protein synthesis and nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein. | 0.420 |
YLR173W | YBR116C | YLR173W | YBR116C | Putative protein of unknown function. | Putative uncharacterized protein YBR116C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the verified gene TKL2. | 0.453 |
YLR173W | YKL071W | YLR173W | YKL071W | Putative protein of unknown function. | Uncharacterized oxidoreductase YKL071W; Putative protein of unknown function; expression induced in cells treated with the mycotoxin patulin, and also the quinone methide triterpene celastrol; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.543 |
YLR173W | YPL067C | YLR173W | YPL067C | Putative protein of unknown function. | Uncharacterized protein YPL067C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL067C is not an essential gene. | 0.429 |
YPL067C | YLR173W | YPL067C | YLR173W | Uncharacterized protein YPL067C; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL067C is not an essential gene. | Putative protein of unknown function. | 0.429 |