STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YLR179CUncharacterized protein YLR179C; Protein of unknown function with similarity to Tfs1p; transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus. (201 aa)    
Predicted Functional Partners:
MRPL28
Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress.
   
 
 0.926
MRPL17
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.890
MRP7
Mitochondrial ribosomal protein of the large subunit.
   
   0.885
MRPL11
Mitochondrial ribosomal protein of the large subunit; localizes to vacuole in response to H2O2.
   
 
 0.879
MRPL33
Mitochondrial ribosomal protein of the large subunit.
   
   0.878
MRPL19
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.877
IMG1
Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome.
   
 
 0.876
RSM23
Mitochondrial ribosomal protein of the small subunit; has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p.
   
 
 0.862
MRP20
Mitochondrial ribosomal protein of the large subunit.
   
 
 0.859
MRP4
Mitochondrial ribosomal protein of the small subunit.
   
 
 0.853
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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