node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MAP1 | MAP2 | YLR244C | YBL091C | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | 0.995 |
MAP1 | RPL25 | YLR244C | YOL127W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | 0.883 |
MAP1 | RPL26A | YLR244C | YLR344W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Ribosomal 60S subunit protein L26A; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26A has a paralog, RPL26B, that arose from the whole genome duplication. | 0.782 |
MAP1 | RPL26B | YLR244C | YGR034W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Ribosomal 60S subunit protein L26B; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26B has a paralog, RPL26A, that arose from the whole genome duplication. | 0.782 |
MAP1 | RPL35A | YLR244C | YDL191W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Ribosomal 60S subunit protein L35A; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35A has a paralog, RPL35B, that arose from the whole genome duplication. | 0.817 |
MAP1 | RPL35B | YLR244C | YDL136W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Ribosomal 60S subunit protein L35B; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35B has a paralog, RPL35A, that arose from the whole genome duplication. | 0.858 |
MAP1 | RPL5 | YLR244C | YPL131W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly; Belongs to the universal ribosomal protein uL18 family. | 0.898 |
MAP1 | RPS15 | YLR244C | YOL040C | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15 and bacterial S19. | 0.851 |
MAP1 | RPS3 | YLR244C | YNL178W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3. | 0.896 |
MAP1 | YNR029C | YLR244C | YNR029C | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Uncharacterized protein YNR029C; Putative protein of unknown function; deletion confers reduced fitness in saline. | 0.893 |
MAP2 | MAP1 | YBL091C | YLR244C | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.995 |
MAP2 | RPL25 | YBL091C | YOL127W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | 0.906 |
MAP2 | RPL26A | YBL091C | YLR344W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Ribosomal 60S subunit protein L26A; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26A has a paralog, RPL26B, that arose from the whole genome duplication. | 0.763 |
MAP2 | RPL26B | YBL091C | YGR034W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Ribosomal 60S subunit protein L26B; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26B has a paralog, RPL26A, that arose from the whole genome duplication. | 0.765 |
MAP2 | RPL35A | YBL091C | YDL191W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Ribosomal 60S subunit protein L35A; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35A has a paralog, RPL35B, that arose from the whole genome duplication. | 0.816 |
MAP2 | RPL35B | YBL091C | YDL136W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Ribosomal 60S subunit protein L35B; homologous to mammalian ribosomal protein L35 and bacterial L29; RPL35B has a paralog, RPL35A, that arose from the whole genome duplication. | 0.815 |
MAP2 | RPL5 | YBL091C | YPL131W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly; Belongs to the universal ribosomal protein uL18 family. | 0.901 |
MAP2 | RPS15 | YBL091C | YOL040C | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15 and bacterial S19. | 0.844 |
MAP2 | RPS3 | YBL091C | YNL178W | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3. | 0.899 |
MAP2 | YNR029C | YBL091C | YNR029C | Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p; Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. | Uncharacterized protein YNR029C; Putative protein of unknown function; deletion confers reduced fitness in saline. | 0.606 |