node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GUF1 | IMG1 | YLR289W | YCR046C | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | 0.969 |
GUF1 | MRP17 | YLR289W | YKL003C | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator. | 0.982 |
GUF1 | MRP7 | YLR289W | YNL005C | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the large subunit. | 0.970 |
GUF1 | MRPL32 | YLR289W | YCR003W | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 0.983 |
GUF1 | MRPL8 | YLR289W | YJL063C | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the large subunit. | 0.971 |
GUF1 | MRPS16 | YLR289W | YPL013C | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the small subunit. | 0.969 |
GUF1 | MRPS9 | YLR289W | YBR146W | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Mitochondrial ribosomal protein of the small subunit. | 0.981 |
GUF1 | RPL25 | YLR289W | YOL127W | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | 0.969 |
GUF1 | RPL5 | YLR289W | YPL131W | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly; Belongs to the universal ribosomal protein uL18 family. | 0.981 |
GUF1 | RPS3 | YLR289W | YNL178W | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3. | 0.981 |
IMG1 | GUF1 | YCR046C | YLR289W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Translation factor GUF1, mitochondrial; Mitochondrial matrix GTPase; associates with mitochondrial ribosomes; important for translation under temperature and nutrient stress; may have a role in translational fidelity; similar to bacterial LepA elongation factor. | 0.969 |
IMG1 | MRP17 | YCR046C | YKL003C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator. | 0.999 |
IMG1 | MRP7 | YCR046C | YNL005C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG1 | MRPL32 | YCR046C | YCR003W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress. | 0.999 |
IMG1 | MRPL8 | YCR046C | YJL063C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the large subunit. | 0.999 |
IMG1 | MRPS16 | YCR046C | YPL013C | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the small subunit. | 0.999 |
IMG1 | MRPS9 | YCR046C | YBR146W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Mitochondrial ribosomal protein of the small subunit. | 0.999 |
IMG1 | RPL25 | YCR046C | YOL127W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23; Belongs to the universal ribosomal protein uL23 family. | 0.998 |
IMG1 | RPL5 | YCR046C | YPL131W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Ribosomal 60S subunit protein L5; nascent Rpl5p is bound by specific chaperone Syo1p during translation; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly; Belongs to the universal ribosomal protein uL18 family. | 0.996 |
IMG1 | RPS3 | YCR046C | YNL178W | Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome. | Protein component of the small (40S) ribosomal subunit; has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; nascent Rps3p is bound by specific chaperone Yar1p during translation; homologous to mammalian ribosomal protein S3 and bacterial S3. | 0.998 |